Results 161 to 170 of about 2,666,341 (347)
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla+15 more
wiley +1 more source
Despite the development of HER2‐targeting drugs such as trastuzumab and T‐DXd, treatment resistance is a substantial challenge, often leading to relapse and distant metastasis.
Qi Zhang+18 more
doaj +1 more source
Remarks on Oophorectomy in the Treatment of Cancer of the Breast [PDF]
Stephanie Boyd
openalex +1 more source
Breast cancer is now the most common cancer of women in the UK and incidence is increasing. Because of major treatment advances and earlier diagnosis over the past 40 years, survival rates have been improving gradually and women diagnosed with breast cancer today are almost twice as likely to survive for 10 years or longer as women 40 years ago ...
openaire +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici+8 more
wiley +1 more source
Two Cases of Lymphangioplasty for the Brawny Arm of Breast Cancer
W. Sampson Handley
openalex +1 more source
A Statistical Report on 2529 Cases of Cancer of the Breast [PDF]
William Harnett
openalex +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert+13 more
wiley +1 more source
IS PAGET'S DISEASE OF THE NIPPLE PRIMARY OR SECONDARY TO CANCER OF THE UNDERLYING BREAST? [PDF]
Alson R. Kilgore
openalex +1 more source