Results 171 to 180 of about 2,749,776 (308)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Molecular and socioeconomic characteristics of inflammatory breast cancer in the Carolina Breast Cancer Study. [PDF]

Breast Cancer Res Treat
Wang Q, Van Alsten SC, Ji X, Salim E, Salazar N, Scott JE, Yang X, Onyenwoke RU, Troester MA, Williams KP.   +9 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Content, Usability, and Utilization of Plain Language in Breast Cancer Mobile Phone Apps: A Systematic Analysis

, 2017
Tamar Ginossar, Sayyed Fawad Ali Shah, Andrew J. West, Joshua M. Bentley, Charlene Caburnay, Matthew W. Kreuter, Anita Y. Kinney   +6 more
openalex   +1 more source

Multigene panel testing for hereditary breast and ovarian cancer in the province of Ontario

, 2020
Jordan Lerner‐Ellis, Chloe Mighton, Conxi Lázaro, Nicholas A. Watkins, Vanessa Di Gioacchino, Andrew Wong, Martin C. Chang, George S. Charames   +7 more
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Perceptions of Breast Cancer: A Cross-Sectional Study Using the Breast Cancer Perception Scale (BPS). [PDF]

Breast Cancer (Auckl)
Kheir O, Baatiah N, Alotaibi A, Dossary S, Dhalaan M, AlMushcab H, Romaihi MA, Darweesh MA, Kabli R, Ghamdi M.   +9 more
europepmc   +1 more source

The role of tumour markers in predicting skeletal metastases in breast cancer patients with equivocal bone scintigraphy [PDF]

, 1999
Andrea Nicolini, Paola Ferrari, A. Sagripanti, Angelo Carpi   +3 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Preferences for return of incidental findings from genome sequencing among women diagnosed with breast cancer at a young age

, 2015
Kimberly A. Kaphingst, Jennifer Ivanovich, Barbara B. Biesecker, Rebecca Dresser, Jiae Seo, L. G. Dressler, Paul J. Goodfellow, Melody S. Goodman   +7 more
openalex   +1 more source