Results 121 to 130 of about 4,382,279 (297)

Practice of opportunistic breast cancer screening and health education among healthcare workers in public health facilities in Ogun state, Southwest Nigeria: a qualitative study of barriers and facilitators

BMC Health Services Research
Background Globally, breast cancer is the most common cancer among women. Nigeria has the highest age-standardized breast cancer mortality rates in Africa, at 25.5 per 100,000.
Tope Olubodun, Abimbola Olaniran, Funmilola Olanike Wuraola, Imran O. Morhason-Bello, Mobolanle Balogun, Taiwo Gboluwaga Amole, Tolulope Soyannwo, Olusegun I. Adebisi, Kamarudeen Olaitan Issa, Solomon Olorunsaiye Olorunfemi, Ephraim Ohazurike, Peter Kingham, Olusegun Isaac Alatise   +12 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Forecasting age-specific breast cancer mortality using functional data models [PDF]

Accurate estimates of future age-specific incidence and mortality are critical for allocation of resources to breast cancer control programs and evaluation of screening programs.
Rob J. Hyndman, Dorota M. Gertig, Bircan Erbas   +2 more
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Visit to Breast test Wales, Cardiff

, 1997
Description of a visit to Visit to Breast test Wales, Cardiff by the National Breast Screening ...
National Breast Screening Programme
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Breast Cancer Awareness and Uptake of Breast Cancer Screening Services Among Undergraduate Female Students in the Oldest University of Tanzania: A Cross-Sectional Study

Breast Cancer: Basic and Clinical Research
Background: Breast cancer is the leading cause of cancer-related death among women worldwide. Mortality from breast cancer can be reduced through early detection and prevention.
Mary Mally, Novatus Tesha, Amani Anaeli
doaj   +1 more source

Efficacy of Ultrasonography in Breast Cancer Screening

Journal of Surgical Ultrasound, 2019
A good screening test should be widely available, inexpensive, and have high sensitivity and specificity. Mammography is the only screening modality proven to reduce the mortality of breast cancer.
doaj   +1 more source

Screening for breast cancer [PDF]

BMJ, 1994
L J, Yeoman, A R, Wilson, A J, Evans
openaire   +2 more sources