Results 111 to 120 of about 2,969,444 (397)

Deep Convolutional Neural Networks for Breast Cancer Histology Image Analysis [PDF]

, 2018
Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists. Computer-aided diagnosis systems showed potential for improving the diagnostic accuracy.
arxiv   +1 more source

MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma [PDF]

, 2013
Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional.
Abba, Martín Carlos, Alberdi, Cecilio G., Croce, María Virginia, Luna, Amalia, Merino, María Emilia, Segal Eiras, Amada   +5 more
core   +3 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Feasibility of radical cardiac‐sparing, treatment planning strategies for patients with locally advanced, non‐small cell lung cancer

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose A set of treatment planning strategies were designed and retrospectively implemented for locally advanced, non‐small cell lung cancer (NSCLC) patients in order to minimize cardiac dose without compromising target coverage goals. Methods Retrospective analysis was performed for 20 NSCLC patients prescribed to 60–66 Gy that received a ...
Joshua P. Kim, Jake Dewalt, Aharon Feldman, Khaled Adil, Benjamin Movsas, Indrin J. Chetty   +5 more
wiley   +1 more source

Characterization of Epstein Barr virus latency pattern in Argentine breast carcinoma. [PDF]

PLoS ONE, 2010
INTRODUCTION: Epstein-Barr virus (EBV)-associated tumors show different expression patterns of latency genes. Since in breast carcinoma this pattern is not yet fully described, our aim was to characterize EBV latency pattern in our EBV positive breast ...
Mario A Lorenzetti, Elena De Matteo, Hugo Gass, Paula Martinez Vazquez, Julia Lara, Pedro Gonzalez, María Victoria Preciado, Paola A Chabay   +7 more
doaj   +1 more source

Telomere loss limits the rate of human epithelial tumor formation [PDF]

arXiv, 2005
Most human carcinomas exhibit telomere abnormalities early in the carcinogenesis process suggesting that crisis caused by telomere shortening may be a necessary event leading to human carcinomas. Epidemiological records of the age at which each patient in a population develops carcinoma are known as age-incidence data; these provide a quantitative ...
arxiv  

Breast Cancer, Version 4.2017, NCCN Clinical Practice Guidelines in Oncology.

The Journal of the National Comprehensive Cancer Network, 2018
Ductal carcinoma in situ (DCIS) of the breast represents a heterogeneous group of neoplastic lesions in the breast ducts. The goal for management of DCIS is to prevent the development of invasive breast cancer.
W. Gradishar, B. Anderson, R. Balassanian, S. Blair, H. Burstein, Amy E. Cyr, A. Elias, W. Farrar, A. Forero, S. Giordano, M. Goetz, L. Goldstein, S. Isakoff, J. Lyons, P. Marcom, I. Mayer, B. McCormick, M. Moran, R. O'Regan, Sameer A. Patel, L. Pierce, E. Reed, K. Salerno, L. Schwartzberg, Amy M. Sitapati, K. Smith, Mary Lou Smith, H. Soliman, G. Somlo, M. Telli, J. Ward, Rashmi Kumar, Dorothy Shead   +32 more
semanticscholar   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

The application of multiple metrics in deformable image registration for target volume delineation of breast tumor bed

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background and purpose For postoperative breast cancer patients, deformable image registration (DIR) is challenged due to the large deformations and non‐correspondence caused by tumor resection and clip insertion. To deal with it, three metrics (fiducial‐, region‐, and intensity‐based) were jointly used in DIR algorithm for improved accuracy ...
Xin Xie, Yuchun Song, Feng Ye, Hui Yan, Shulian Wang, Xinming Zhao, Jianrong Dai   +6 more
wiley   +1 more source

Granulomatous reaction associated with breast carcinoma: A report of two cases

Saudi Journal of Medicine and Medical Sciences, 2014
The presence of a granulomatous reaction in association with a breast carcinoma is a rare phenomenon. We present two cases of breast carcinoma, invasive ductal and invasive lobular carcinoma in which a non-caseating granulomatous response was present ...
Timor Alalshee, Tahira Hamed, Sheikh M Shafi   +2 more
doaj   +1 more source