Results 111 to 120 of about 1,254,223 (252)

Evaluation of human cytomegalovirus antigen expression in invasive breast carcinoma in a population of Iranian patients

Infectious Agents and Cancer, 2017
Background The role of human cytomegalovirus (HCMV) in the development of breast carcinoma is questionable. The aim of this study was to evaluate the expression of the immediate early antigen (IE) of HCMV in breast carcinoma and its association with some
Fereshteh Mohammadizadeh, Fatemeh Mahmudi   +1 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy [PDF]

, 2011
Background: Resistance to trastuzumab is a clinical problem, partly due to overriding activation of MAPK/PI3K signalling. Sprouty-family proteins are negative regulators of MAPK/PI3K signalling, but their role in HER2-therapy resistance is unknown ...
Faratian Dana, Sims, Andrew H., Sims Andrew H., Simon P. Langdon, Langdon, Simon P., Kay Charlene, Dana Faratian, Charlene Kay, Um InHwa, Harrison David J., David J. Harrison, Um, Inhwa, Simon P Langdon, David J Harrison, Langdon Simon P., Faratian, Dana, Mullen, Peter, Andrew H. Sims, Kay, Charlene, Kay, Charlene; id_orcid, Mullen Peter, Andrew H Sims, Peter Mullen, Harrison, David J., Inhwa Um   +24 more
core   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Diversity of matriptase expression level and function in breast cancer [PDF]

, 2011
This work was funded by Cancer Research UK Program Grant (C157/A9148).Overexpression of matriptase has been reported in a variety of human cancers and is sufficient to trigger tumor formation in mice, but the importance of matriptase in breast cancer ...
Sproul, Duncan, Muir, Morwenna, Peter Mullen (171093), Faratian Dana, Brunton, Valerie G, Morwenna Muir, Brunton Valerie G., Dana Faratian (171110), Muir, Morwenna; id_orcid, Frame, Margaret C., David J. Harrison (171106), Muir Morwenna, Dana Faratian, Valerie G Brunton, Andrew R Kinnaird, Andrew R. Kinnaird (171104), Valerie G. Brunton, Brunton, Valerie G., Kinnaird, Andrew R., Duncan Sproul, Morwenna Muir (171098), David J. Harrison, Harrison David J., Frame, Margaret C, Duncan Sproul (3186), Sproul Duncan, Andrew R. Kinnaird, Arkadiusz Welman (171085), Kinnaird Andrew R., Harrison, David J, Arkadiusz Welman, Margaret C Frame, David J Harrison, Faratian, Dana, Mullen, Peter, Margaret C. Frame (171119), Kinnaird, Andrew R, Welman Arkadiusz, Frame Margaret C., Welman, Arkadiusz, Margaret C. Frame, Mullen Peter, Valerie G. Brunton (171114), Peter Mullen, Harrison, David J.   +44 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Survival analysis of 1148 women diagnosed with breast cancer in Southern Iran [PDF]

, 2009
Background: while there has been much research regarding risk factors and prognostic factors for breast cancer in general, research specific to Iran is sparse.
Talei, Abdolrasoul, Rezaianzadeh, Abbas, Daniel Reidpath, Reidpath Daniel, Reidpath, D, Peacock, J, Hosseini, SV, Talei Abdolrasoul, Hosseini, Seyed Vahid, Hosseini, Seyed Vahid, Seyed Hosseini, Rezaianzadeh Abbas, Davood Mehrabani, Talei, A, Janet Peacock, Hoseini Seyed, Mehrabani, D, Mehrabani Davood, Rezaianzadeh, A, Peacock, Janet, Hosseini, S.V, Peacock Janet, Seyed Vahid Hosseini, Peacock, J.L, Mehrabani, Davood, Reidpath, Daniel, Abdolrasoul Talei, Reidpath, DD, Abbas Rezaianzadeh   +28 more
core   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Breast Cancer in Ardabil Province in the North-West of Iran: an Epidemiological Study [PDF]

Breast cancer accounts for about 26% of all newly diagnosed cancers in women aged 20 to 59 years. As part of a basic program for cancer control, the present cross sectional descriptive study was conducted with the objective of determining the ...
علیمحمدی, حسین, پورفرضی, فرهاد, امانی, فیروز, لطفی, ایلشن, مظاهری, عفت, فولادی, نسرین   +5 more
core   +1 more source

Histopathology of Breast Cancer in the Central Hospital, Warri, Delta State, Nigeria.

Sokoto Journal of Medical Laboratory Science, 2019
Breast cancer is the top major cause of demise among women. This study captured the histologic sorts of breast malignant tumors among women who underwent breast biopsy in the Department of Pathology, Central Hospital, and Warri, Delta State, Nigeria ...
Anibor, E.*
doaj