Results 111 to 120 of about 3,686,577 (308)

Determination Of Breast Density Using Fuzzy Logic

پیاورد سلامت, 2014
Background and Aim: The risk of breast cancer increases directly in line with breast density. Therefore, it is important to pay more attention to denser breasts in order to detect abnormalities.
Mostafa Langarizadeh, Rozi Mahmud
doaj  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Conversion of immunohistochemical markers and breast density are associated with pathological response and prognosis in very young breast cancer patients who fail to achieve a pathological complete response after neoadjuvant chemotherapy

Cancer Management and Research, 2019
Yue Zhao,1 Xiaolei Wang,2 Yuanxi Huang,1 Xianli Zhou,2 Dongwei Zhang31Department of Breast Surgery, The Tumor Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China; 2Department of In-Patient Ultrasound, The Second ...
Zhao Y, Wang X, Huang Y, Zhou X, Zhang D
doaj  

Tailored 3D breast models for development of microwave based breast tumor screening

Finnish Journal of eHealth and eWelfare
Portable breast monitoring devices, which could be used outside the hospital and even for self-monitoring of risk groups, are considered as promising eHealth applications for future telemedicine. Microwave technique is one of the most promising emerging
Mariella Särestöniemi, Daljeet Singh, Jarmo Reponen, Teemu Myllylä   +3 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Accuracy of Abbreviated Breast MRI in Diagnosing Breast Cancer in Women with Dense Breasts Compared with Standard Imaging Modalities

Saudi Journal of Medicine and Medical Sciences
Background: Breast density is an independent risk factor for breast cancer and affects the sensitivity of mammography screening. Therefore, new breast imaging approaches could benefit women with increased breast density in early cancer detection and ...
Areej S. Aloufi, Nuha Khoumais, Fayka Ahmed, Sara Hosawi, Sameera Sulimani, Deema Abunayyan, Fadiah Alghamdi, Samar Alshehri, Malak Alsaeed, Rasha Sahloul, Reem Sabir, Elaine F. Harkness, Susan M. Astley   +12 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Breast density assessment using breast tomosynthesis images

, 2016
In this work we evaluate an approach for breast density assessment of digital breast tomosynthesis (DBT) data using the central projection image. A total of 348 random cases (both FFDM CC and MLO views and DBT MLO views) were collected using a Siemens ...
Timberg, Pontus, Dustler, Magnus, Petersson, Hannie, Magnus Dustler, Hannie Petersson, Sartor, Hanna, Daniel Förnvik, Fieselmann, Andreas, Lång, Kristina, Hanna Sartor, Zackrisson, Sophia, Andreas Fieselmann, Kristina Lång, Sophia Zackrisson, Pontus Timberg, Förnvik, Daniel, Petersson, Hannie,, Dustler, Magnus,, Zackrisson, Sophia,, Timberg, Pontus,, Förnvik, Daniel,, Lång, Kristina,, Sartor, Hanna,, Fieselmann, Andreas,, Lund University.   +24 more
core   +1 more source

Do pathological parameters differ with regard to breast density and mode of detection in breast cancer? The Malmö Diet and Cancer Study.

, 2015
Our aim was to study how breast density relates to tumor characteristics in breast cancer with emphasis on mode of detection. Among 17,035 women in the Malmö Diet and Cancer Study 826 incident cases have been diagnosed (1991-2007).
Zackrisson, Sophia, Werner Hartman, Linda, Sartor, Hanna, Borgquist, Signe, Zackrisson, Sophia,, Werner Hartman, Linda,, Sartor, Hanna,, Borgquist, Signe,, Lund University.   +8 more
core   +2 more sources