Results 11 to 20 of about 778,689 (289)

Dalpiciclib and pyrotinib in women with HER2-positive advanced breast cancer: a single-arm phase II trial

open access: yesNature Communications, 2023
CDK4/6 inhibitors have shown a synergistic effect with anti-HER2 therapy in hormone receptor (HR)-positive and HER2-positive breast cancer (BC). In this phase 2 study (NCT04293276), we aim to evaluate a dual-oral regimen of CDK4/6 inhibitor dalpiciclib ...
Min Yan   +13 more
doaj   +1 more source

Insulin-like growth factor 2 receptor is a key immune-related gene that is correlated with a poor prognosis in patients with triple-negative breast cancer: A bioinformatics analysis

open access: yesFrontiers in Oncology, 2022
BackgroundImmunotherapy plays an important role in the treatment of triple-negative breast cancer (TNBC). This study aimed to identify immune-related genes that are associated with the prognosis of patients with TNBC as possible targets of immunotherapy,
Ying Zhong   +9 more
doaj   +1 more source

ABC of breast diseases: Breast cancer [PDF]

open access: yesBMJ, 2000
Breast cancers are derived from the epithelial cells that line the terminal duct lobular unit. Cancer cells that remain within the basement membrane of the elements of the terminal duct lobular unit and the draining duct are classified as in situ or non-invasive.
J R, Sainsbury   +2 more
openaire   +2 more sources

Breast fibromatosis, an unusual breast disease [PDF]

open access: yesJournal of Surgical Case Reports, 2017
Fibromatosis is a benign tumor that rarely affects the breast and is an unusual site for its occurrence. Whilst the definite etiology of breast fibromatosis is unclear, it may present itself following surgical trauma or silicone implant. Wide local excision with adequate safety margins is considered the standard of care. We review three cases of breast
Abdelwahab, Khaled   +6 more
openaire   +2 more sources

Effects of prenatal professional breastfeeding education for the family

open access: yesScientific Reports, 2022
Mastering the correct breastfeeding posture remains a challenge for many new mothers. Generalized pregnancy breastfeeding education plays a role in helping mothers master breastfeeding positions and prevent nipple damage.
Haifeng Gao   +7 more
doaj   +1 more source

Breast-feeding and benign breast disease [PDF]

open access: yesJournal of Obstetrics and Gynaecology, 2011
Benign breast disease (BBD) is very common among women in their fertile age, but its correlation with breast reproductive function remains unclear. Our study aimed to investigate the relation between BBD and breast-feeding. We collected data on 105 women with BBD and 98 controls, focusing on their reproductive history and breast-feeding.
Bernardi, S.   +5 more
openaire   +4 more sources

A randomized and open-label phase II trial reports the efficacy of neoadjuvant lobaplatin in breast cancer

open access: yesNature Communications, 2018
Triple-negative breast cancer (TNBC) is one of the most aggressive and difficult to treat types of breast cancer. Here, a phase 2 clinical trial in TNBC patients reveals that the addition of lobaplatin to docetaxel and epirubicin regime improves pCR and ...
Xiujuan Wu   +8 more
doaj   +1 more source

Overexpression of kinesin superfamily members as prognostic biomarkers of breast cancer

open access: yesCancer Cell International, 2020
Background Kinesin superfamily (KIFs) has a long-reported significant influence on the initiation, development, and progress of breast cancer. However, the prognostic value of whole family members was poorly done.
Tian-Fu Li   +9 more
doaj   +1 more source

Thyroid hemiagenesis and Hashimoto’s thyroditis—diagnostic and treatment pitfalls

open access: yesWorld Journal of Surgical Oncology, 2017
Background Thyroid hemiagenesis (TH) is a rare congenital disease with absence of a thyroid lobe; most patients have no clinical symptoms. The etiology of TH remains unclear.
Minghao Wang   +6 more
doaj   +1 more source

Dyslipidemia is associated with a poor prognosis of breast cancer in patients receiving neoadjuvant chemotherapy

open access: yesBMC Cancer, 2023
Background Lipid metabolism disorders may be involved in the occurrence and development of breast cancer. This study aimed to investigate the serum lipid changes during neoadjuvant chemotherapy for breast cancer and the effect of dyslipidemia on the ...
Youzhao Ma   +4 more
doaj   +1 more source

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