Results 41 to 50 of about 3,482,222 (258)

Potential Usefulness a Coronal View using an Automated Breast Ultrasound System in Detecting Breast Lesions

open access: yesEuropean Journal of Breast Health
Objective: An automated breast ultrasound system (ABUS) combined with screening mammography has increased cancer detection rates; however, supplemental ABUS use has increased recall rates.
Megumi Suzuki   +5 more
doaj   +1 more source

Clinicopathological profile of breast cancer from Chhattisgarh India: A single-center hospital-based study

open access: yesJournal of Family Medicine and Primary Care, 2023
Background: Global breast cancer incidence is increasing at an annual rate of 3·1%. Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%).
Niraj Kumar Srivastava   +3 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Artificial intelligence-driven prediction and design of cell-penetrating peptides for advanced drug delivery system

open access: yesFrontiers in Pharmacology
BackgroundCell-penetrating peptides (CPPs) are promising delivery vectors for transporting therapeutic agents across cellular membranes. However, their rational design remains challenging because the relationship between peptide sequence and ...
Bo Yu   +5 more
doaj   +1 more source

Galactocele due to drugs prescribed after augmentation mammoplasty: a case report and literature review [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2016
Augmentation mammaplasty is a common and safe plastic surgery procedure, but it is not free from complications. Galactocele after augmentation mammaplasty is rarely described in the literature.
Mauricio Schneider Salomone Viaro   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Personalized approach to diagnosis verification and pathogenetic therapy in benign breast diseases (literature review)

open access: yes, 2023
The review presents data on the tactics of managing patients with benign breast diseases aimed at reducing the incidence of breast cancer. Particular attention is paid to the use of non-hormonal herbal preparations with a favorable safety profile, the ...
Tatyana Yu. Pestrikova   +3 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Clinical Features of Breast Cancer in South Korean Patients with Germline TP53 Gene Mutations [PDF]

open access: yes, 2021
Purpose: Li-Fraumeni syndrome (LFS) is a rare autosomal cancer syndrome caused by a germline mutation in the TP53 gene. Breast cancer in LFS patients is of various subtypes; however, limited data are available on the clinicopathological features of these
정준   +14 more
core   +1 more source

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