Results 41 to 50 of about 1,272,372 (129)

Targeting chondroitin sulfate suppresses macropinocytosis of breast cancer cells by modulating syndecan‐1 expression

Molecular Oncology, Volume 18, Issue 10, Page 2569-2585, October 2024.
This study reveals CHPF's role in breast cancer cell survival under nutrient deprivation, proposing a model where TGF‐β and CHPF increase cell surface SDC1, promoting macropinocytosis in cancer cells. The chondroitin sulfate‐specific binding peptide, C6S‐p, shows promise in counteracting CHPF effects by binding to CS‐SDC1, leading to SDC1 degradation ...
Hung‐Rong Yen, Wen‐Chieh Liao, Chia‐Hua Chen, Ying‐Ai Su, Ying‐Wei Huang, Chi Hsiao, Yu‐Lun Chou, Yin‐Hung Chu, Pin‐Keng Shih, Chiung‐Hui Liu   +9 more
wiley   +1 more source

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer? [PDF]

, 2013
Shear wave elastography (SWE) shows promise as an adjunct to greyscale ultrasound examination in assessing breast masses. In breast cancer, higher lesion stiffness on SWE has been shown to be associated with features of poor prognosis.
Thomson, Kim, Petra Rauchhaus, Patsy Whelehan, Rauchhaus, Petra, Andrew Evans, Vinnicombe, Sarah, Michie, Caroline O, Caroline O. Michie, Kim Thomson, Purdie, Colin A, Whelehan, Patsy; id_orcid, Alastair Thompson, Jordan, Lee B., Sarah Vinnicombe, Lee B. Jordan, Evans, Andrew, Thompson, Alastair, Colin A. Purdie   +17 more
core   +1 more source

Atypical ductal hyperplasia is a multipotent precursor of breast carcinoma [PDF]

, 2019
The current model for breast cancer progression proposes independent “low‐grade (LG) like” and “high‐grade (HG) like” pathways but lacks a known precursor to HG cancer.
Campbell, IG, Doyle, Maria, Kylie L Gorringe, Mann, GB, Hill, Prue, Mann, G. Bruce, David L Goode, Wajiha Sufyan, Magnus Zethoven, Miligy, IM, Murugasu, Anand, Emad A Rakha, Elder, K, Islam M Miligy, Green, Andrew R, Green, AR, Goode, DL, Thio, N, Semple, T, Stephen B Fox, Gorringe, KL, Prue Hill, Anand Murugasu, G Bruce Mann, Goode, David L., Campbell, Ian G., Ian G Campbell, Sufyan, W, Kader, T, David J Byrne, Rakha, Emad A, Andrew R Green, Byrne, DJ, Thio, Niko, Gorringe, Kylie L., Pang, JMB, Jia‐Min B Pang, Sufyan, Wajiha, Murugasu, A, Hill, P, Elder, Kenneth, Tanjina Kader, Semple, Timothy, Rakha, EA, Kenneth Elder, Maria Doyle, Zethoven, M, Fox, Stephen B., Kader, Tanjina, Doyle, M, Byrne, David J., Zethoven, Magnus, Pang, Jia-Min B., Miligy, Islam M, Niko Thio, Timothy Semple, Fox, SB   +56 more
core   +1 more source

Bridging Smart Nanosystems with Clinically Relevant Models and Advanced Imaging for Precision Drug Delivery

Advanced Science, Volume 11, Issue 14, April 10, 2024.
This comprehensive review explores recent advancements in intracellular NP delivery, emphasizing the design of personalized nano‐drug‐carriers for clinical applications. It highlights the importance of evaluating drug efficacy and delivery efficiency in physiologically relevant ex vivo human tissue models.
Qiaoxia Zhou, Qiongliang Liu, Yan Wang, Jie Chen, Otmar Schmid, Markus Rehberg, Lin Yang   +6 more
wiley   +1 more source

Extracellular vesicles as a promising source of lipid biomarkers for breast cancer detection in blood plasma

Journal of Extracellular Vesicles, Volume 13, Issue 3, March 2024.
Abstract Extracellular vesicles (EVs), including exosomes and microvesicles, mediate intercellular communication in cancer, from development to metastasis. EV‐based liquid biopsy is a promising strategy for cancer diagnosis as EVs can be found in cancer patients’ body fluids. In this study, the lipid composition of breast cancer‐derived EVs was studied
Erika Dorado, Maria Luisa Doria, Anika Nagelkerke, James S. McKenzie, Stefania Maneta‐Stavrakaki, Thomas E. Whittaker, Jeremy K. Nicholson, Raoul Charles Coombes, Molly M. Stevens, Zoltan Takats   +9 more
wiley   +1 more source

BreastScreen Australia monitoring report 2011-2012 [PDF]

, 2014
Presents the latest national statistics on BreastScreen, which aims to reduce illness and death resulting from breast cancer through organised screening to detect cases of unsuspected breast cancer in women, thus enabling early intervention.
Biljana Tanevska, Justin Harvey, Wendy Ho, Alison Budd   +3 more
core  

BreastScreen Australia monitoring report 2010-2011 [PDF]

, 2013
SummaryBreastScreen Australia aims to reduce illness and death resulting from breast cancer through organised screening to detect cases of unsuspected breast cancer in women, thus enabling early intervention.

core  

Overexpression of malic enzyme is involved in breast cancer growth and is correlated with poor prognosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 6, March 2024.
Abstract Malic enzyme (ME) genes are key functional metabolic enzymes playing a crucial role in carcinogenesis. However, the detailed effects of ME gene expression on breast cancer progression remain unclear. Here, our results revealed ME1 expression was significantly upregulated in breast cancer, especially in patients with oestrogen receptor ...
Wan‐Chung Hu, Yi‐Fang Yang, Ching‐Feng Cheng, Ya‐Ting Tu, Hong‐Tai Chang, Kuo‐Wang Tsai   +5 more
wiley   +1 more source

Metastasis of Ductal Breast Carcinoma to the Vagina – A Case Report [PDF]

, 2013
Primary cancers of the vagina are rare, and so vaginal tumours are likely to represent metastasis from another site. Although breast cancer is a common malignancy, it rarely gives rise to vaginal metastases.
Anna Candida Andrade de Camaret, Leila Cristina Soares   +1 more
core  

The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines [PDF]

, 2014
Copyright @ 2014 the authors. This article is made available through the Brunel Open Access Publishing Fund. It is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution ...
Slijepcevic, P, Terry Roberts, Yasaei, H, Roberts, T, Azadeh Motevalli, Motevalli, A, Predrag Slijepcevic, Sara Anjomani Virmouni, Hemad Yasaei, Virmouni, SA   +9 more
core   +1 more source