Results 111 to 120 of about 298,071 (357)
Advanced Science, EarlyView.This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du +13 more
wiley +1 more source
Angewandte Chemie International Edition, Volume 61, Issue 51, December 19, 2022., 2022 Corramycin is a novel natural product produced by the myxobacterium Corallococcus coralloides. The structure, extraordinary total synthesis and biosynthesis of the antibiotic is described for the first time. Its promise as an in vivo septicemia model, the absence of cross‐resistance with commonly used antibiotic classes, and the lack of cytotoxicity ...
Cédric Couturier +32 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare +7 more
wiley +1 more source
Вопросы современной педиатрии, 2013 In order of assess the results of introduction of the programs aimed at maintenance and support of the breast-feeding it is necessary to use uniform indicators, which guarantee consistency, reliability and comparability of the data.
L. V. Abol'yan +2 more
doaj +1 more source
Assessment of Knowledge and Practice on Breast Feeding Among Mothers of Children Aged Less Than Two Years and Associated Factors in Areka Town, Wolita Zone, Southern Ethiopia, 2018 [PDF]
, 2021 World health organization guideline recommend that continuous frequent and on-demand breast feeding until two years of age and beyond is essential for the child as well as the mother.
Yeheyis, Tomas
core +1 more source
SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
Advanced Science, EarlyView.SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi +11 more
wiley +1 more source
Accessible ecophysiological tools for seabird conservation
Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 32, Issue 12, Page 1983-2002, December 2022., 2022 Abstract Seabirds are the most endangered avian taxa on Earth, with over a third of species globally threatened. To help slow their decline, conservation physiology seeks to determine how seabird responses to climatic and anthropogenic threats influence demographic processes, but it is not widely utilized in monitoring.
Edin A. Whitehead, Brendon J. Dunphy
wiley +1 more source
HIPPURIC ACID IN THE URINE OF NORMAL BREAST-FEED INFANTS [PDF]
, 1911 Samuel Amberg
openalex +1 more source
Advanced Science, EarlyView.In CLas‐infected D. citri, CLas lowers 20E levels initially, relieving the suppression of ETH release. The subsequent increase in ETH levels upregulates its receptor DcETHR and activates the JH signaling pathway. The signaling cascade of 20E‐ETH/ETHR‐JH along with miR‐210, targeting DcETHR, boost female fecundity in CLas+ D.
Xiaoge Nian +8 more
wiley +1 more source