Results 161 to 170 of about 282,442 (237)

The contribution of extracellular RNA and its derived biomaterials in disease management

open access: yesBMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei   +8 more
wiley   +1 more source

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

How Companies With Industrial Symbiosis Business Models Can Contribute to the Mainstreaming of Industrial Symbiosis

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Companies incorporating industrial symbiosis in their business models (ISBMs) play important roles in the realization of IS solutions. This paper explores how this group can also influence contextual conditions for the wider adoption of these solutions, thus contributing to their mainstreaming.
Kristina Nyström, Murat Mirata
wiley   +1 more source

Prospective associations between breast feeding, metabolic health, inflammation and bone density in women with prior gestational diabetes mellitus. [PDF]

open access: yesBMJ Open Diabetes Res Care
Hebeisen I   +9 more
europepmc   +1 more source

Improving trans‐cinnamic acid production in a model cyanobacterium

open access: yesBiotechnology Progress, Volume 41, Issue 2, March/April 2025.
Abstract trans‐Cinnamic acid (tCA) is a precursor in the synthesis of many high‐value compounds with bio‐active qualities useful in applications like medicine, polymers, and cosmetics. Currently tCA is produced by industrial chemical synthesis from fossil fuels or cost‐prohibitive isolation from terrestrial plants.
Darcy Hunstiger   +3 more
wiley   +1 more source

Harnessing cell aggregates for enhanced adeno‐associated virus manufacturing: Cultivation strategies and scale‐up considerations

open access: yesBiotechnology Progress, EarlyView.
Abstract The possibility to produce recombinant adeno‐associated virus (rAAV) by adherent HEK293T cells was studied in a stirred tank bioreactor (STR) culture of cell aggregates. A proof‐of‐concept of rAAV production was successfully demonstrated in a process where single cells were first expanded, then cell aggregates were formed by dilution into a ...
Brian Ladd   +2 more
wiley   +1 more source

Characterization of large transgene integrations in Chinese hamster ovary cells using a bioengineered mammalian transposase

open access: yesBiotechnology Progress, EarlyView.
Abstract We present the first use of a bioengineered mammalian transposase system derived from Myotis lucifugus (bMLT) for integration of expression vectors into the CHO genome, focusing on GFP and trastuzumab production. Initially, CHO‐K1 cells are transfected with a GFP reporter and varying amounts of bMLT DNA or mRNA.
Nicolas Marx   +10 more
wiley   +1 more source

Online monitored characterization of Phocaeicola vulgatus for organic acid production using anaerobic microtiter plate cultivations

open access: yesBiotechnology Progress, Volume 41, Issue 2, March/April 2025.
Abstract Phocaeicola vulgatus (formerly Bacteroides vulgatus), an anaerobic gut bacterium, produces several organic acids. Research on P. vulgatus is still in its infancy. However, a detailed understanding of P. vulgatus growth and metabolism is essential for its assessment as an organic acid producer.
Laura Keitel   +4 more
wiley   +1 more source

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