Results 281 to 290 of about 298,071 (357)
Single Cell Protein Production From Ethanol: Model‐Based Bioreactor Operation at Industrial Scale
Biotechnology and Bioengineering, EarlyView.ABSTRACT Alternative fermentation feedstocks such as ethanol can be produced from CO2 via electrocatalytic processes that coproduce O2. In this study, industrial‐scale fermentation of ethanol with pure O2 for single cell protein (SCP) production was studied using a modeling approach.
Eduardo Almeida Benalcázar +6 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Escherichia coli accumulates acetate as a byproduct in fast growth aerobic conditions when using glucose as carbon source. This phenomenon, known as overflow metabolism, has negative impacts on cell growth and protein expression, also causes carbon loss during biosynthesis in most microbial production scenarios. In this study, we regarded the “
Jianli Zhang +8 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Recombinant adeno associated virus (rAAV) vectors have become popular delivery vehicles for in vivo gene therapies, but demand for rAAVs continues to outpace supply. Platform processes for rAAV production are being developed by many manufacturers, and transient chemical transfection of human embryonic kidney 293 (HEK293) cells is currently the
Erica A. Green +9 more
wiley +1 more source
Prospective associations between breast feeding, metabolic health, inflammation and bone density in women with prior gestational diabetes mellitus. [PDF]
BMJ Open Diabetes Res CareHebeisen I +9 more
europepmc +1 more source
The paucity of breast-feeding in an urban clinic population.
, 1980 P D Magnus, Silvia Galindo
openalex +1 more source
Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells
Biotechnology and Bioengineering, EarlyView.ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson +9 more
wiley +1 more source
Physiology and Robustness of Yeasts Exposed to Dynamic pH and Glucose Environments
Biotechnology and Bioengineering, EarlyView.The authors investigated how three Saccharomyces cerevisiae strains respond to dynamic substrate and pH oscillations using dynamic microfluidic single‐cell cultivation (dMSCC) and intracellular biosensors. By combining performance and robustness analysis of selected intracellular parameters, growth and morphological analysis, the authors identified ...
Luca Torello Pianale +3 more
wiley +1 more source
The contribution of extracellular RNA and its derived biomaterials in disease management
BMEMat, EarlyView.The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei +8 more
wiley +1 more source