Results 321 to 330 of about 2,742,191 (376)

Association Between Feeding Problems and Gastrointestinal Symptoms, Language, and Developmental History in Adults With Angelman Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Angelman syndrome (AS) is a neurodevelopmental disorder characterized by severe developmental delays, typical facial features, ataxia, seizures, speech impairments, sleeping difficulties, and a happy demeanor. Caregivers of individuals with AS often report feeding problems, with difficulties including issues with obesity, failure to gain ...
Ciara Cassidy   +6 more
wiley   +1 more source

High Dose Vitamin A Supplementation of Breast-Feeding Indonesian Mothers: Effects on the Vitamin A Status of Mother and Infant

open access: bronze, 1993
Rebecca J. Stoltzfus   +6 more
openalex   +1 more source

Artificial Intelligence Software Changes Rare Disease Testing Strategy in Real Time: An International Case Series Using Face2Gene

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genetic disorders commonly share features such as developmental delays, cognitive impairment, and behavioral challenges, yet many conditions also present unique dysmorphic features that distinguish them. Performing a thorough medical and family history and a detailed physical exam with attention to dysmorphic features is often the first step ...
Natasha L. Rudy   +15 more
wiley   +1 more source

Establishment of a patient‐derived drug‐resistant oral squamous cell carcinoma animal model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Patient‐derived xenograft (PDX) tissues from less‐responsive groups (larger tumors) were serially passaged. Sequential passaging and drug exposure in PDX models recapitulated clinical tumor evolution, enabling the development of drug‐resistant oral squamous cell carcinoma (OSCC) models. This study can offer methodological insights for precision therapy
Chuanni Feng   +8 more
wiley   +1 more source

Gold Nanoclusters as Smart Nanoplatforms for Targeted Cancer Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
A folic acid‐targeted gold nanocluster platform is developed for tumor‐specific delivery and radiofrequency (RF)‐triggered release of doxorubicin. Enhanced uptake, nuclear localization, and therapeutic efficacy are confirmed in 2D and 3D spheroid models.
Samad Mussa Farkhani   +6 more
wiley   +1 more source

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai   +5 more
wiley   +1 more source

Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta

open access: yesThe Anatomical Record, EarlyView.
Abstract Early life behaviors have a profound role in shaping adult craniofacial morphology. During early life, all mammals undergo the dynamic transition from suckling to mastication, a period coinciding with rapid cranial biomineralization. Osteogenesis imperfecta (OI), a genetic disorder that impacts the production of type I collagen, disrupts ...
Courtney A. Miller   +2 more
wiley   +1 more source

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