Results 81 to 90 of about 311,821 (303)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Factors Associated with Discotinuation of Exclusive Breast Feeding by First Time Mothers

نشریه پرستاری ایران, 2011
Backgrounfd & Aim: Maternal exclusive breast feeding for the first 6 months of newborn's life has been recommended by World Health Organization. Recently, a high incidence of breast feeding discontinuation has been reported in Iran.
Rahmatnejad L, Bastani F
doaj  

Socially sensitive lactation: Exploring the social context of breastfeeding [PDF]

, 2012
Many women report difficulties with breastfeeding and do not maintain the practice for as long as intended. Although psychologists and other researchers have explored some of the difficulties they experience, fuller exploration of the relational ...
A Dakroury, A Finch, A Huyssen, AT Olmstead, AT Thrall, B Girard, CJ Hamelink, CJ Hamelink, D Kellner, EL Daniel, ES Herman, I Volkmer, JS Milloy, K Jaspers, K Tester, M Halbwachs, M Hodgkin, M Renes, O Hoerschelmann, P Connerton, P Nora, P Ricoeur, PM Taylor, RA Mcchesney, RC Vincent, T Todorov, TC Mitchell, TR Weeks, V Mayer-Schönberger, W Preston Jr, WG Sebald   +30 more
core   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

MODERN APPROACHES TO ASSESSMENT OF THE BREAST-FEEDING BY THE EXAMPLE OF THE CHECHEN REPUBLIC AND THE REPUBLIC OF INGUSHETIA

Вопросы современной педиатрии, 2013
In order of assess the results of introduction of the programs aimed at maintenance and support of the breast-feeding it is necessary to use uniform indicators, which guarantee consistency, reliability and comparability of the data.
L. V. Abol'yan, P. M. Evloeva, E. I. Barteneva   +2 more
doaj   +1 more source

Pemasyarakatan Air Susu Ibu (Asi) Eksklusif melalui Penyuluhan [PDF]

, 1997
The objectives of this study were: (1) to evaluate and compare changes and differences on the knowledge and attitude toward Exclusive Breast Feeding, among pregnant and breast feeding mothers exposed to various campaign techniques; (2) to assess and ...
Ajik, S. (Suharti), Djoerban, B. (Badrijah), Rahanto, S. (Sugeng), Sarwanto, S. (Sarwanto), Soeparmanto, P. (Paiman), Sumarsih, S. (Sumarsih), Widjiartini, W. (Widjiartini)   +6 more
core  

Breastfeeding status during the first two years of infants’ life and its risk factors based on BASNEF model structures in Isfahan [PDF]

, 2013
Background: Breastfeeding depends on social and cultural conditions of societies. Behavior,Attitude, Subjective Norms, Enabling Factors (BASNEF) model is one of the comprehensive models of behavior study, especially in developing countries.
Badleh, M.T., Charkazi, A., Hasanzadeh, A., Miraeiz, S.Z., Razzaghnejad, A., Shahnazi, H.   +5 more
core   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

High levels of childhood obesity observed among 3- to 7-year-old New Zealand Pacific children is a public health concern. [PDF]

, 2018
This cross-sectional, community-based survey was designed to assess attained growth and body composition of 3- to 7-y-old Pacific children (n = 21 boys and 20 girls) living in Dunedin, New Zealand, and to examine nondietary factors associated with the ...
Ailsa Goulding, Anderson, Andrea M. Grant, Barbara E. Guthrie, Bathgate, Bindon, Chinn, Cole, Cole, Deckelbaum, Dwyer, Elaine L. Ferguson, Ellis, Figueroa-Colon, Fiona K. Gordon, Freedman, Frisancho, Gortmaker, Goulding, Higgins, Jebb, Kimm, Lohman, Lunar Corporation, Margarey, Ogden, Ramirez, Rossner, Rush, Russell, Salesa, Swinburn, Taylor, Teavekura-Emma Henry, Tonkin, Tyrrell, Viliami Toafa, Ward, Williams, Williams   +39 more
core   +1 more source

Breast-feeding - The view of women who breast-feed

Jornal de Pediatria, 1995
This is a qualitative study, the result of questions about breast-feeding in terms of the meaning it has for the woman who experiences it. The phenomenological theoretical background led to understand breast-feeding based on the dimension of a being who breast-feeds. Thus, we sought the discourse of women using the following guiding question: "What did
openaire   +2 more sources