Results 61 to 70 of about 16,055 (244)

Clinical Utility of promoter methylation of the tumor suppressor genes DKK3, and RASSF1A in breast cancer patients

open access: yesEgyptian Journal of Medical Human Genetics, 2018
Background: DNA methylation is the commonest known epigenetic change that results in silencing of tumor suppressor genes. Promoter methylation of tumor suppressor genes has the potential for early detection of breast cancer.
Marwa H. Saied   +3 more
doaj   +1 more source

Expression and intracellular localization of FKHRL1 in mammary gland neoplasms. [PDF]

open access: yes, 2004
FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in breast tumors still remains unclear.
Akagi, Tadaatsu   +8 more
core   +1 more source

Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis

open access: yesNano Select, Volume 7, Issue 1, January 2026.
Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee   +5 more
wiley   +1 more source

Breast Findings in Females With Beckwith–Wiedemann Syndrome

open access: yesPediatric Blood &Cancer, Volume 73, Issue 1, January 2026.
ABSTRACT Beckwith–Wiedemann syndrome (BWS) is an overgrowth condition caused by epigenetic defects on chromosome 11p15. Children with BWS have a predisposition to embryonal tumors such as Wilms tumor and hepatoblastoma. However, few reports of breast tumors in females with BWS have been published and the risk of malignancy and need for screening ...
Liron D. Grossmann   +5 more
wiley   +1 more source

Infiltrating Ductal Carcinoma Arising in Fibroadenoma and Associated Proliferative Mammary Disease in a 38 Years Old Female -A Rare Case Report [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2017
Infiltrating ductal carcinoma arising in a fibroadenoma is a rare incidental finding. Incidence is 0.002-0.0125%. Women having proliferative disease without atypia have a twofold elevation in their risk for subsequent invasive breast cancer.
Hemlata T. Kamra   +4 more
doaj  

Aberrant DNA methylation of cancer-related genes in giant breast fibroadenoma: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Giant fibroadenoma is an uncommon variant of benign breast lesions. Aberrant methylation of CpG islands in promoter regions is known to be involved in the silencing of genes (for example, tumor-suppressor genes) and appears to be an early ...
Orozco Javier I   +5 more
doaj   +1 more source

Spectral discrimination of breast pathologies in situ using spatial frequency domain imaging [PDF]

open access: yes, 2013
Introduction: Nationally, 25% to 50% of patients undergoing lumpectomy for local management of breast cancer require a secondary excision because of the persistence of residual tumor.
Barth, Richard J   +9 more
core   +5 more sources

Automated Segmentation and Analysis of Histopathological Breast Cancer Images for Enhanced IDC Diagnosis and Assessment Using MobileNetV2+U‐Net With Label Propagation

open access: yesInternational Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Breast cancer remains the most common cancer type among women, with invasive ductal carcinoma (IDC) responsible for almost 80% of cases. The exact histopathological segmentation of IDC is the premise of diagnosis, but manual observation of hematoxylin and eosin (H&E) stained slides is very time‐consuming and results in interobserver variability.
Vijaylaxmi Inamdar   +2 more
wiley   +1 more source

Fibroadenoma in axillary supernumerary breast: case report

open access: yesSão Paulo Medical Journal
CONTEXT: Supernumerary breast tissue may be affected by the same diseases and alterations that compromise topical breast tissue. Nevertheless, reports of fibroadenoma in supernumerary breast tissue in the axillae are rare.
Délio Marques Conde   +4 more
doaj   +1 more source

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