Results 61 to 70 of about 16,055 (244)
Background: DNA methylation is the commonest known epigenetic change that results in silencing of tumor suppressor genes. Promoter methylation of tumor suppressor genes has the potential for early detection of breast cancer.
Marwa H. Saied +3 more
doaj +1 more source
Expression and intracellular localization of FKHRL1 in mammary gland neoplasms. [PDF]
FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in breast tumors still remains unclear.
Akagi, Tadaatsu +8 more
core +1 more source
Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis
Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee +5 more
wiley +1 more source
Breast Findings in Females With Beckwith–Wiedemann Syndrome
ABSTRACT Beckwith–Wiedemann syndrome (BWS) is an overgrowth condition caused by epigenetic defects on chromosome 11p15. Children with BWS have a predisposition to embryonal tumors such as Wilms tumor and hepatoblastoma. However, few reports of breast tumors in females with BWS have been published and the risk of malignancy and need for screening ...
Liron D. Grossmann +5 more
wiley +1 more source
Infiltrating Ductal Carcinoma Arising in Fibroadenoma and Associated Proliferative Mammary Disease in a 38 Years Old Female -A Rare Case Report [PDF]
Infiltrating ductal carcinoma arising in a fibroadenoma is a rare incidental finding. Incidence is 0.002-0.0125%. Women having proliferative disease without atypia have a twofold elevation in their risk for subsequent invasive breast cancer.
Hemlata T. Kamra +4 more
doaj
Aberrant DNA methylation of cancer-related genes in giant breast fibroadenoma: a case report
Introduction Giant fibroadenoma is an uncommon variant of benign breast lesions. Aberrant methylation of CpG islands in promoter regions is known to be involved in the silencing of genes (for example, tumor-suppressor genes) and appears to be an early ...
Orozco Javier I +5 more
doaj +1 more source
Spectral discrimination of breast pathologies in situ using spatial frequency domain imaging [PDF]
Introduction: Nationally, 25% to 50% of patients undergoing lumpectomy for local management of breast cancer require a secondary excision because of the persistence of residual tumor.
Barth, Richard J +9 more
core +5 more sources
Breast cancer remains the most common cancer type among women, with invasive ductal carcinoma (IDC) responsible for almost 80% of cases. The exact histopathological segmentation of IDC is the premise of diagnosis, but manual observation of hematoxylin and eosin (H&E) stained slides is very time‐consuming and results in interobserver variability.
Vijaylaxmi Inamdar +2 more
wiley +1 more source
Fibroadenoma in axillary supernumerary breast: case report
CONTEXT: Supernumerary breast tissue may be affected by the same diseases and alterations that compromise topical breast tissue. Nevertheless, reports of fibroadenoma in supernumerary breast tissue in the axillae are rare.
Délio Marques Conde +4 more
doaj +1 more source

