Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li +9 more
wiley +1 more source
Clinical Management of Breast Implant Illness and Breast Implant-Associated Somatic Symptom Disorder (BIA-SSD): Case Examples of Treatment Options. [PDF]
Bresnick SD.
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Breast-implant associated unicentric castleman disease: a case report. [PDF]
Shyamsundar S +12 more
europepmc +1 more source
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao +14 more
wiley +1 more source
Adverse Event Reports and Safety Measures for Breast Implant-associated Anaplastic Large Cell Lymphoma in Japan. [PDF]
Akaishi K, Maeda H.
europepmc +1 more source
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu +7 more
wiley +1 more source
Health Communication Patterns in Breast Implant Illness Content on TikTok: A DISCERN-based Analysis by Creator Type. [PDF]
Kastury MR +7 more
europepmc +1 more source
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma +10 more
wiley +1 more source
Microbial Contamination-Mediated Inflammation Is a Major Contributor of Breast Implant Complications: Prospective Analysis of 631 Samples. [PDF]
Kerschbaumer C +7 more
europepmc +1 more source

