Results 51 to 60 of about 65,313 (302)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

BellaGel breast implant: 6-Year results of a prospective cohort study

open access: yesArchives of Plastic Surgery, 2020
Background This is the first clinical study conducted among Asian women using breast implants manufactured by an Asian company. Four-year data regarding the safety and efficacy of BellaGel breast implants have already been published, and we now report 6-
Joon Seok Oh   +8 more
doaj   +1 more source

Early Complications After Radical Operations in Breast Cancer Patients [PDF]

open access: yes, 2020
Breast cancer is one of the most common Malignancies in women. In many cases, a major component of complex treatment for breast cancer is surgery - radical mastectomy or radical breast resection.The aim of the work – to investigate the frequency and ...
Baranova, A. (Anna)   +2 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1989
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1272/thumbnail ...

core   +4 more sources

The Breast Tumor Microenvironment: Could Silicone Breast Implant Elicit Breast Carcinoma?

open access: yesBreast Cancer: Targets and Therapy, 2021
Eduardo Fleury,1 Cristiane Nimir,2 Gabriel Salum D’Alessandro3 1Service of Radiology, IBCC – Instituto Brasileiro de Controle do Câncer, São Paulo, SP, Brazil; 2Service of Pathology, FEMME – Laboratório da Mulher, S ...
Fleury E, Nimir C, D'Alessandro GS
doaj  

The Breast Implant Controversy: A Prism for Reform [PDF]

open access: yes, 2001
The author argues that regulatory blunders and the litigation explosion pertaining to breast implants highlight defects in U.S.
Yang, Benson
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Incidence of surgical site infection following mastectomy with and without immediate reconstruction using private insurer claims data [PDF]

open access: yes, 2015
OBJECTIVE: The National Healthcare Safety Network classifies breast operations as clean procedures with an expected 1–2% surgical site infection (SSI) incidence.
Ball, Kelly E   +7 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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