Results 81 to 90 of about 940,505 (307)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation

, 2018
Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, lacking effective targeted therapies, and whose underlying mechanisms are still unclear.
Liu, Jingjing, Yang, Qianxi, Zhang, Jin, Hu, Yunhui, Zhao, Hui, Pan, Teng, Liu, Lei, Yagüe, Ernesto   +7 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Multiple polyurethane implant punctures during fat grafting: case report and review of the literature

BMC Surgery, 2020
Background Breast augmentation with implants continues to be the most popular aesthetic surgical procedure performed worldwide. Fat grafting may improve the results of breast augmentation and breast reconstruction with implants.
Dmitry Batiukov, V. Podgaiski, D. Mikulich, S. Kalinin   +3 more
doaj   +1 more source

Breast Implants and Radiation

Seminars in Plastic Surgery, 2019
AbstractOne of the most influential factors in the success of breast reconstruction is whether or not radiation therapy has or will be performed. While traditional teaching is that all breasts treated with radiation therapy must be reconstructed with an autologous component, many reconstructive surgeons perform implant-based breast reconstruction ...
Alexander F, Mericli, Safa E, Sharabi
openaire   +3 more sources

The value of patients' expectation on breast oncoplastic surgery

, 2014
Breast Unit Barretos Cancer Hospital Sao Paulo Co-ordinator - Breast Oncoplastic Training CenterSchool of Medicine of Botucatu PGDGOM Sao ...
Vieira, Rene A. C., Zucca-Matthes, Gustavo   +1 more
core   +1 more source

Changes in articular cartilage after meniscectomy and meniscus replacement using a biodegradable porous polymer implant [PDF]

, 2010
Purpose: To evaluate the long-term effects of implantation of a biodegradable polymer meniscus implant on articular cartilage degeneration and compare this to articular cartilage degeneration after meniscectomy.
Arend Jan Schouten, Buma, Pieter,, Schouten, Arend Jan,, Hannink, Gerjon, Buma, P., Buma, Pieter, Tienen, Tony G. van,, Tienen, T.G. van, Gerjon Hannink, Pieter Buma, Tienen, Tony G. van, Hannink, G.J., Schouten, A.J., Tony G. van Tienen, van Tienen, Tony G., Schouten, Arend Jan, de Mulder, E.L., Hannink, Gerjon,   +17 more
core   +6 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Rotation of microtextured anatomical breast implants: A retrospective series of 134 reconstructions

JPRAS Open
Background: Anatomically shaped breast implants are widely used in implant-based breast reconstruction because of their ability to restore breast contour and projection.
Tarik Ihrai, Alice Roosen, Dominique Lanvin, Philippe Giordano   +3 more
doaj   +1 more source

Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast [PDF]

, 2008
Introduction To investigate the predictive value of clinical and biological markers for a pathological complete remission after a preoperative dose-dense regimen of doxorubicin and docetaxel, with or without tamoxifen, in primary operable breast cancer ...
Sinn, Hans-Peter, Sibylle Loibl, Jens-Uwe Blohmer, Jörn Hilfrich, Eidtmann, Holger, Jackisch, Christian, Minckwitz, Gunter von, Elisabeth Merkle, Hilfrich, Jörn, Caputo, Angelika, Angelika Caputo, Merkle, Elisabeth, Dan Costa, Serban, Blohmer, Jens-Uwe, Gunter von Minckwitz, Raab, Günter, German Breast Group (GBG), [Study group], Christian Jackisch, Hans-Peter Sinn, Serban D Costa, Holger Eidtmann, Loibl, Sibylle, Manfred Kaufmann, von Minckwitz, Gunter, null null, Günter Raab, Costa, Serban D., Kaufmann, Manfred   +27 more
core   +2 more sources