Results 171 to 180 of about 53,346 (263)

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Large-scale manufacturing of precisely patterned flexible soft tissue implants with high porosity. [PDF]

open access: yesBiofabrication
Shabazz A   +6 more
europepmc   +1 more source

Hemp (Cannabis sativa L.) Seed Protein and Its Hydrolysate Promote Bone Formation via the SMAD‐Dependent BMP Pathway

open access: yesiNew Medicine, EarlyView.
ABSTRACT Objective With the global increase in aging populations, the prevalence of osteoporosis is rising. Current preventive and therapeutic strategies remain limited. The present study aimed to investigate the effects of hemp seed protein (HSP) and its hydrolysis‐derived bioactive peptides (HPH) on osteogenic differentiation and to elucidate their ...
Yan Wang   +14 more
wiley   +1 more source

Black phosphorus‐based photothermal disruption of cancer‐associated fibroblast barriers and tumor‐associated macrophage targeting to enhance anti‐PD‐L1 immunotherapy in triple‐negative breast cancer

open access: yesInterdisciplinary Medicine, EarlyView.
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan   +12 more
wiley   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

open access: yesInterdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu   +13 more
wiley   +1 more source

Modeling Health Effects of Alternative Treatment Options during Surgical Delay to Inform Prioritization of Surgical Care. [PDF]

open access: yesMed Decis Making
van Alphen A   +7 more
europepmc   +1 more source

Diffusion MRI of the Body: Beyond PGSE‐EPI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Diffusion magnetic resonance imaging (dMRI) is a widely used clinical imaging technique which is sensitive to changes in tissue microstructure including cellularity, perfusion, and tissue damage. DMRI has been used in whole‐body imaging as well as in targeted imaging of every major anatomical region.
Matthew T. Cherukara   +6 more
wiley   +1 more source

Epidermal inclusion cyst after breast reduction mammoplasty. [PDF]

open access: yesRadiol Case Rep
Park A, Lugo-Rodriguez V, Diaz KF.
europepmc   +1 more source

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