Results 71 to 80 of about 1,018,704 (304)

Autonomous Navigation of Pollen‐Inspired Magnetic Microrobots for Biomedical Applications

Advanced Robotics Research, EarlyView.
A sunflower pollen‐inspired magnetic microrobot enables controlled rolling navigation in vessel‐like environments. Its open geometry reduces hydrodynamic drag, while vision‐based closed‐loop control, shortest‐path planning, and reinforcement learning support target‐reaching and maze navigation with microrobot‐scale accuracy, highlighting a route toward
Ali Anil Demircali, Abdurrahim Yilmaz, Meysam Keshavarz, Jinshi Zhao, Ara Darzi, Eric Yeatman, Burak Temelkuran   +6 more
wiley   +1 more source

Evaluation of the Oncologic Outcomes of Breast Cancer According to the Smooth Implants Versus Textured Implants: A Systematic Review and Meta-analysis [PDF]

International Journal of Scientific Research in Dental and Medical Sciences
Background and aim: Concerns about the potential carcinogenic effects of breast implants, particularly those with textured surfaces, have recently been raised by an increasing number of reports of anaplastic large cell lymphoma associated with breast ...
Sheida Sabbagh Seddigh, Maryam Fathi, Seyedeh Solmaz Riazi, Yasamin Zoljalali, Fateme Hemati, Sadaf Akbari   +5 more
doaj   +1 more source

ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer. [PDF]

, 2012
INTRODUCTION: Estrogen receptor-α (ER) and human epidermal growth factor receptor 2 (HER2) positivity are inversely correlated by standard criteria. However, we investigated the quantitative relation between ER and HER2 expression at both RNA and protein
Yarnold, J, Drury, Suzanne, Barrett-Lee, P, Hills, Margaret, Salter, J, Lawrence, D, Harnett, AM, Cuzick, J, Earl, H, Sestak, I, Ma, NCRIABCT, Georges Sumo, A'Hern, R, Sestak, Ivana, Barrett-Lee, Peter Jeffrey, Dowsett, M, A'Hern, Roger, Robinson, A, Perren, T, Johnson, L, Harris, Adrian, George, WD, Bliss, JM, Dodwell, D, null null, Peter Barrett-Lee, Price, D, Foster, L, Poole, C, Isabel Pinhel, Suzanne Drury, Fernando, I, Dowsett, Mitch, Cuzick, Jack, Judith M Bliss, Barrett-Lee, Peter, Sumo, G, Raina, V, Hills, M, Roger A'Hern, Ivana Sestak, Adrian Harris, Janine Salter, Jack Cuzick, Bliss, Judith M., Brunt, AM, Peto, J, Drury, S, Bliss, Judith M, Sumo, Georges, Margaret Hills, Mitch Dowsett, Pinhel, Isabel, Harris, A, NCRI Adjuvant Breast Cancer Trial Management Group, Bliss, M, Pinhel, I, Salter, Janine   +57 more
core   +2 more sources

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Evaluate the Implant Failure Rate of Radiotherapy Administered after Mastectomy in Breast Cancer Patients: A Systematic Review and Meta-analysis [PDF]

International Journal of Scientific Research in Dental and Medical Sciences
Background and aim: It is currently unclear which risk factors lead to problems with breast implant reconstruction and failure of prosthetic reconstruction. The connection between radiation and complications has not yet been comprehensively investigated.
Yasaman Shariati, Somaye Jamali, Majid Hajizadeh   +2 more
doaj   +1 more source

The evolution of breast implants

Plastic Surgery, 2002
The present review traces the evolution of breast implants over the past 50 years. During the early years (from 1951 to 1962), a number of different sponges were used for breast augmentation. The first of these was Ivalon, a polyvinyl alcohol sponge. Other sponges were introduced subsequently, including Etheron (a poly-ether sponge popularized by Dr ...
openaire   +1 more source

Mammographic breast density refines Tyrer-Cuzick estimates of breast cancer risk in high-risk women: findings from the placebo arm of the International Breast Cancer Intervention Study I [PDF]

, 2014
Introduction: Mammographic density is well-established as a risk factor for breast cancer, however, adjustment for age and body mass index (BMI) is vital to its clinical interpretation when assessing individual risk.
Howell, Anthony; id_orcid, Jennifer Stone, Cuzick, Jack, Pinney, E, Jane Warwick, Pinney, Elizabeth, Stone, J, Stone, Jennifer, Cuzick, J, Ruth ML Warren, Duffy, Stephen W., Warwick, J, Warren, Ruth ML, Warren, RML, Howell, A, Birke, Hanna, Duffy, SW, Jack Cuzick, Duffy, Stephen W, Bretnall, Adam, Warren, Ruth, Birke, [Unknown], Warwick, Jane, Howell, Anthony, Brentnall, AR, Elizabeth Pinney, Adam R Brentnall, Stephen W Duffy, Anthony Howell, Hanna Birke, Brentnall, Adam R., Birke, H   +31 more
core   +2 more sources

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Influence of stromal–epithelial interactions on breast cancer in vitro and in vivo

, 2019
Stromal cell-secreted chemokines including CCL2 have been implicated in the primary tumor microenvironment, as mediators of tumor cell migration, proliferation, and angiogenesis.
Dwyer, Róisín M., Hartmann, Marion C., Khan, Sonja, Potter, Shirley M., Boyle, Marie P., Curran, Catherine E., Kerin, Michael J.   +6 more
core   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source