Results 111 to 120 of about 26,753 (256)
Eduardo De Faria Castro Fleury,1,2 Michele Rodrigues da Silva Junqueira,2 Tiago Sarmet Esteves Teixeira,2 Pryscilla Alves Ferreira,2 Giulia Matheus e Castro,1 Bruna Aguiar Portugal Viotti2 1Radiology, Faculdade de Ciências Médicas da Santa Casa de São ...
De Faria Castro Fleury E +5 more
doaj
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang +12 more
wiley +1 more source
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Postmarket Study of Silimed's Silicone Gel Polyurethane Foam-covered Breast Implants: Interim Results (2018-2024). [PDF]
Munhoz AM.
europepmc +2 more sources
Solid Harmonic Wavelet Bispectrum for Image Analysis
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source
Breast Implants: Biomaterials, Surfaces, Biocompatibility-A Biomedical Engineering Perspective. [PDF]
Auguścik A +9 more
europepmc +1 more source
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu +12 more
wiley +1 more source

