Results 121 to 130 of about 1,088,016 (258)

Study on Food Antigens Transferred into Breast Milk [PDF]

open access: yes, 2007
74検体の母乳中に移行した食物抗原(オボムコイド、オボアルブミン、β一ラクトグロブリン、カゼイン及びグリアジン)をELISA法にて分析した。その結果、母乳中に各食物抗原は、11-34%の頻度、12.8-44.3ng/m1の最大濃度で存在していた。母乳中に移行した食物抗原の濃度は母乳のIgA濃度と正相関が認められ、5種類の食物抗原特異的IgAが全ての母乳に存在していた。これらの結果より、母乳中に移行した食物抗原はIgAと免疫複合体を形成していることが推測された。また ...
Isomura, Haruhiko, Totani, Masayuki
core  

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Influence of Holder Pasteurisation on DHA concentrations in human breast milk

open access: yes, 2008
Human breast milk is universally recognized as the optimal food for term and pre-term infant. In the absence of an adequate supply of breast milk, mothers are offered term breast milk from human milk banks, which collect, process and store milk from ...
L. Marvulli   +5 more
core   +1 more source

The inhibition of HIV-1 activity by crude mucus and purified mucin (mucous glycoproteins) from saliva, breast milk and the cervical tract of normal subjects, HIV positive individuals and patients with HIV-AIDS [PDF]

open access: yes, 2007
Includes bibliographical references (leaves 140-161).Human saliva, breast milk and cervical secretions contain several non-immunological components including mucins (mucous glycoproteins), which protect the gastrointesinal and female reproductive tracts ...
Habte, Habtom Haileselassie
core   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

open access: yesAdvanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du   +10 more
wiley   +1 more source

Day/night fluctuations of breast milk bioactive factors and microbiome

open access: yesFrontiers in Nutrition
IntroductionHuman breast milk is a sophisticated and complex biological fluid that provides crucial nutritional, immunological, and microbial benefits to infants.
Melissa A. Woortman   +13 more
doaj   +1 more source

The ‘Got Milk’ project. The timing of lactogenesis phase II: the impact of mother-infant proximity [PDF]

open access: yes, 2009
This study explores the effects of mother-infant close-contact while on the postnatal ward on the maternal perception of the onset of lactogenesis phase II (LII).The 'Got Milk?' project utilized a sub-sample of 49 mothers of newly delivered infants ...
Robinson, Lyn
core  

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

open access: yesAdvanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl   +20 more
wiley   +1 more source

The Association Between Maternal Dietary Intake and the Risk of Heavy Metals in Human Breast Milk in Korea

open access: yesToxics
Heavy metals (HMs) persist in the environment and enter the human body via various pathways. Once stored in adipose tissue, they can be transferred to breast milk, posing risks to infants. Moreover, maternal diet plays a key role in influencing HM levels
Nalae Moon   +4 more
doaj   +1 more source

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

open access: yesAdvanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang   +11 more
wiley   +1 more source

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