Results 231 to 240 of about 1,896,405 (407)
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu+9 more
wiley +1 more source
Abstract Background Calreticulin (CRT), an endoplasmic reticulum–resident protein generally overexpressed in cancer cells, is associated with radiation resistance. CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8‐diacetoxy‐4‐methylcoumarin, DAMC) and modifies the activity of a ...
Amit Verma+6 more
wiley +1 more source
BREAST-MILK JAUNDICE AND ORAL CONTRACEPTIVES [PDF]
Yuk-ki Wong, B. S. B. Wood
openalex +1 more source
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu+22 more
wiley +1 more source
Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis
Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade+2 more
wiley +1 more source
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui+15 more
wiley +1 more source
The Effect of "Humanised" Milks and Supplemented Breast Feeding on The Faecal Flora of Infants
C. L. Bullen, P Tearle, M. G. STEWART
openalex +1 more source
454 BREAST MILK CHOLESTEROL, PHYTOSTEROL, AND TOTAL FAT [PDF]
Margot J. Mellies+2 more
openalex +1 more source