Results 41 to 50 of about 172,514 (265)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Microorganisms, 2023 Breastfeeding is essential in the first months of a newborn’s life. Breast milk is a source of crucial macronutrients, prebiotic oligosaccharides, and potential probiotic strains of bacteria.
Daniela Mollova +3 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Heavy Metal Nanoparticle Detection in Human and Formula Milk
FoodsBreast milk is the natural source of nutrition for infants, but while it supports their health, it can also be a potential source of toxic inorganic particulate matter, and this applies to both breast milk and industrially produced milk.
Antonietta Morena Gatti +13 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Breast milk reduced umbilical cord separation and bacterial colonization: Article Review. [PDF]
International Egyptian Journal of Nursing Sciences and ResearchOwing to cultural traditions and variations in global health care practices, umbilical cord care practices vary across countries. The use of topical human breast milk has been proposed as an important cord care regimen, because antimicrobial and healing ...
Ebtsam Mahrous +3 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Breast milk beta-glucuronidase levels in hyperbilirubinemia
The Turkish Journal of Pediatrics, 2001 Breast milk beta-glucuronidase was thought to be one of the etiological factors in the pathogenesis of late-onset breast-milk jaundice, but results of these studies are conflicting.
S Yiğit, G Ciliv, C Aygün, G Erdem
doaj
The Turkish Journal of Pediatrics, 2019 Breast milk is a well-balanced ideal nutritional source with high bioavailability for infants. As being a fresh, biological and dynamic product, changes in the breast milk during these storage periods have been the subject of ongoing research.
Murat Konak +5 more
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Determination of Knowledge and Views of Married Women Aged 18-49 About Breast Milk Banks
Çocuk Dergisi, 2021 Objective: This study was performed descriptively to determine th eknowledge and views of married women aged 18-49 regarding breast milk banks. Materials and Methods: The study was carried out at two Family Health Centers (FHC) in Sivas city center.
İlknur Yıldız +2 more
doaj +1 more source