Results 71 to 80 of about 1,088,016 (258)

Impact of Maternal Nutrient Consumption on Human Milk Macro Nutrient Composition: A Cross-Sectional Study

Çocuk Dergisi
Objective: To increase the production of human milk, mothers must have an adequate, balanced, and healthy diet. This study investigated the effect of maternal food consumption on the macronutrient composition of breast milk. Methods: This cross-sectional
Fatma Şule Bilgiç, Gülçin Bozkurt, Emine Asuman Çoban   +2 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Comparative Study on Lipid Dynamics in Maternal Breast Milk between Preterm and Term Infants of Han Ethnicity in Northwestern China [PDF]

Shipin Kexue
Objective: To conduct comparative analysis of the dynamic trend of breast milk lipid composition across different lactation stages in mothers of preterm and term infants with the aim of providing a basis for optimizing feeding strategies for preterm ...
FENG Yan, WANG Xinyue, XUE Jianlan, LUO Xiaoqin, SU Li, LI Ting, DUAN Sufang, LIU Biao, SITU Wenyou
doaj   +1 more source

Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in Botswana.

, 2007
BACKGROUND: Infants of human immunodeficiency virus (HIV)-infected women have high mortality, but the immunologic integrity and protection afforded by the breast milk of HIV-infected women is unknown.
Rahkola, Jeremy T, Shapiro, Roger L, Janoff, Edward N, Stevens, Lisa, Smeaton, Laura, Wester, Carolyn, Arimi, Peter, Ndase, Patrick, Makhema, Joseph, Montano, Monty, Asmelash, Aida, Lockman, Shahin, Thior, Ibou, Kim, Soyeon, Moffat, Claire, Essex, Max   +15 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

IMMUNOGENIC FACTORS OF THE BREAST MILK DURING ITS PROLONGED STORAGE UNDER LOW TEMPERATURES

Вопросы современной педиатрии, 2013
The data on the influence of the prolonged low temperatures effect (-20°C) on the immunogenic factors of the breast milk is shown in the article. The received during the study new data on the stability of the secretory immunoglobulin A in the breast milk
E. I. Kondrat'eva, D. E. Khapacheva, A. I. Tlif, L. A. Podporina, S. V. Storozhuk   +4 more
doaj   +1 more source

The Content of African Diets is Adequate to Achieve Optimal Efficacy with Fixed-Dose Artemether-Lumefantrine: A Review of the Evidence. [PDF]

, 2008
A fixed-dose combination of artemether-lumefantrine (AL, Coartem(R)) has shown high efficacy, good tolerability and cost-effectiveness in adults and children with uncomplicated malaria caused by Plasmodium falciparum.
Nathan Mulure, Abdulla, Salim, Kokwaro, Gilbert, Salim Abdulla, Mulure, Nathan, Ndong, A, Zulfiqarali G Premji, Ndong, A., Alice Ndong, Gilbert Kokwaro, Abdulla, S., Ndong, Alice, Mulure, N., Nwaiwu, Obiyo, Premji, Zul, Nwaiwu, O., Ogutu, Bernhards, Falade, C.O., Premji, Zulfiqarali G, Falade, Catherine O, Catherine O Falade, Sagara, Issaka, Sagara, I., Obiyo Nwaiwu, Ogutu, B., Bernhards Ogutu, Premji, Z.G., Kokwaro, G., Issaka Sagara   +28 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source