Results 111 to 120 of about 344,924 (336)

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Oral Soft Tissue Metastasis from Breast Cancer as the Only Primary Source: Systematic Review

open access: yesAvicenna Journal of Medicine
Background Breast cancer is one of the most lethal neoplasms causing death. Oral cavity is the rare site of distant metastasis from breast cancer.
Nausheen Aga   +5 more
doaj   +1 more source

Syntaxin-1 and Insulinoma-Associated Protein 1 Expression in Breast Neoplasms with Neuroendocrine Features. [PDF]

open access: yesPathol Oncol Res, 2021
Turkevi-Nagy S   +5 more
europepmc   +1 more source

Explainable machine learning for neoplasms diagnosis via electrocardiograms: an externally validated study [PDF]

open access: yesarXiv
Background: Neoplasms remains a leading cause of mortality worldwide, with timely diagnosis being crucial for improving patient outcomes. Current diagnostic methods are often invasive, costly, and inaccessible to many populations. Electrocardiogram (ECG) data, widely available and non-invasive, has the potential to serve as a tool for neoplasms ...
arxiv  

Segmentation of Breast Regions in Mammogram Based on Density: A Review [PDF]

open access: yesIJCSI International Journal of Computer Science Issues, Vol. 9, Issue 4, No 2, July 2012, 2012
The focus of this paper is to review approaches for segmentation of breast regions in mammograms according to breast density. Studies based on density have been undertaken because of the relationship between breast cancer and density. Breast cancer usually occurs in the fibroglandular area of breast tissue, which appears bright on mammograms and is ...
arxiv  

Cylindroma of the Breast: Case Report of a Rare Breast Neoplasm

open access: yesCureus
The majority of breast malignancies are either ductal or lobular tumors. A rare benign neoplasm of adnexal origin, cylindroma of the breast, was first described 23 years ago, and 21 cases have been documented in the literature since then. We report a case of a breast cylindroma on a 62-year-old woman who presented with a nodule first detected by a ...
Papaoikonomou, Angelos Michail   +4 more
openaire   +2 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

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