Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
New Observations on Distribution of Neoplasms of Female Breast in Certain European Countries [PDF]
, 1965 A. J. LEA
openalex +1 more source
Polyphenols as Promising Drugs against Main Breast Cancer Signatures
Antioxidants, 2017 Breast cancer is one of the most common neoplasms worldwide, and in spite of clinical and pharmacological advances, it is still a clinical problem, causing morbidity and mortality. On the one hand, breast cancer shares with other neoplasms some molecular
María Losada-Echeberría +3 more
doaj +1 more source
A clinical diagnostic test on the detection of sentinel lymph node metastasis in breast neoplasms using a 1-step RT-PCR. [PDF]
Gland Surg, 2022 Shang J +5 more
europepmc +1 more source
Dermatomyositis. Adenocarcinoma of Male Breast. Detection of Antibodies to the Neoplasm in the Serum [PDF]
, 1967 P.W.M. Copeman +2 more
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: Analisar a eficácia da suspensão de carvão inerte na marcação de lesões impalpáveis mamárias e as alterações morfológicas associadas ao seu uso, além de determinar se há ou não prejuízo na interpretação destas lesões pelo patologista.
Teresa Cristina Santos Cavalcanti +6 more
doaj +1 more source
Syntaxin-1 and Insulinoma-Associated Protein 1 Expression in Breast Neoplasms with Neuroendocrine Features. [PDF]
Pathol Oncol Res, 2021 Turkevi-Nagy S +5 more
europepmc +1 more source
The Feasibility of Clinical and Radiological Screening for Breast Neoplasm [PDF]
, 1975 D L Asbury, P G Barker
openalex +1 more source