Results 131 to 140 of about 439,387 (353)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Immunoreaction at 43 kDa with Anti‐ubiquitin Antibody in Breast Neoplasms [PDF]

open access: hybrid, 1997
Keiichi Iwaya   +11 more
openalex   +1 more source

Cylindroma of the Breast: Case Report of a Rare Breast Neoplasm

open access: yesCureus
The majority of breast malignancies are either ductal or lobular tumors. A rare benign neoplasm of adnexal origin, cylindroma of the breast, was first described 23 years ago, and 21 cases have been documented in the literature since then. We report a case of a breast cylindroma on a 62-year-old woman who presented with a nodule first detected by a ...
Papaoikonomou, Angelos Michail   +4 more
openaire   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

PHD finger protein 10 promotes cell proliferation by regulating CD44 transcription in gastric cancer

open access: yesHeliyon
PHD finger protein 10 (PHF10) plays an important role in the tumorigenesis of gastric cancer (GC). However, clinical significance and underlying molecular mechanisms about PHF10 is unclear.
Zhiyuan Fan   +6 more
doaj  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Fine-needle aspiration cytology of extramammary neoplasms metastatic to the breast [PDF]

open access: bronze, 2005
R Shukla   +4 more
openalex   +1 more source

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