Results 161 to 170 of about 1,763,654 (403)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Lesões impalpáveis da mama marcadas com suspensão de carvão: avaliação de aspectos anatomopatológicos, viabilidade de interpretação e resposta inflamatória

open access: yesRevista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Analisar a eficácia da suspensão de carvão inerte na marcação de lesões impalpáveis mamárias e as alterações morfológicas associadas ao seu uso, além de determinar se há ou não prejuízo na interpretação destas lesões pelo patologista.
Teresa Cristina Santos Cavalcanti   +6 more
doaj   +1 more source

Breast density in MRI: an AI-based quantification and relationship to assessment in mammography [PDF]

open access: yesarXiv
Mammographic breast density is a well-established risk factor for breast cancer. Recently there has been interest in breast MRI as an adjunct to mammography, as this modality provides an orthogonal and highly quantitative assessment of breast tissue.
arxiv  

Immunoreaction at 43 kDa with Anti‐ubiquitin Antibody in Breast Neoplasms [PDF]

open access: hybrid, 1997
Keiichi Iwaya   +11 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

PHD finger protein 10 promotes cell proliferation by regulating CD44 transcription in gastric cancer

open access: yesHeliyon
PHD finger protein 10 (PHF10) plays an important role in the tumorigenesis of gastric cancer (GC). However, clinical significance and underlying molecular mechanisms about PHF10 is unclear.
Zhiyuan Fan   +6 more
doaj  

Home - About - Disclaimer - Privacy