Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Effect of resveratrol on doxorubicin resistance in breast neoplasm cells by modulating PI3K/Akt signaling pathway [PDF]
, 2018 J Chen, Junyun Bai, K T Yang
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Type of Recurrence, Cause of Death and Second Neoplasms among 737 Patients with Ductal Carcinoma In Situ of the Breast—15-Year Follow-Up [PDF]
, 2022 Anna Niwińska, Michał Kunkiel
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Evaluation of the Systemic and Regional Antibiotic Therapy Effectiveness as Part of Complex Therapy in Patients with Locally Spread Breast Cancer [PDF]
, 2019 In recent years, breast cancer is the most common oncologic pathology and the most common cause of disability among women in developed countries.The aim of the study.
Bondar, O. (Oleksandr)
core
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Death of human tumor endothelial cells in vitro through a probable calcium-associated mechanism induced by bevacizumab and detected via a novel method [PDF]
, 2010 We isolated three dimensional cell clusters from fresh human solid tumors and also isolated human neoplastic and normal lymphatic cells. Cells were cultured for 96 hours with and without bevacizumab and other agents.
Constance Rueff-Weisenthal +2 more
core +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Performed a Qualitative and Quantitative of Breast Self-Examination: a Checklist Approach
Journal of Community Health Research, 2013 Introduction: Breast neoplasia is the most common cancer among women in both developed and developing countries. Over 1.15 million women in the world detecting with breast neoplasia each year and the mortality rate is 502,000 cases from this cancer.
Mahshid Bokaie, Mohammad Hassan Lotfi
doaj
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Human medicines European public assessment report (EPAR): Zirabev, bevacizumab, Colorectal Neoplasms,Breast Neoplasms,Carcinoma, Non-Small-Cell Lung,Carcinoma, Renal Cell,Uterine Cervical Neoplasms, Date of authorisation: 14/02/2019, Revision: 1, Status: Authorised [PDF]
, 2019 openalex +1 more source