Results 171 to 180 of about 855,325 (373)

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

A Multi-Modal AI System for Screening Mammography: Integrating 2D and 3D Imaging to Improve Breast Cancer Detection in a Prospective Clinical Study [PDF]

arXiv
Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence system integrating FFDM, synthetic mammography, and DBT to provide breast-level predictions and bounding-box ...
arxiv  

Analysis of Breast Cancer Mortality in the US-1975 to 2019 [PDF]

IMPORTANCE: Breast cancer mortality in the US declined between 1975 and 2019. The association of changes in metastatic breast cancer treatment with improved breast cancer mortality is unclear.
Alagoz, Oguzhan, Berry, Donald A, Caswell-Jin, Jennifer L, Hampton, John M, Huang, Hui, Huang, Xuelin, Jayasekera, Jinani, Kurian, Allison W, Lee, Sandra J, Li, Yisheng, Lu, Ying, Mandelblatt, Jeanne S, Munoz, Diego, Plevritis, Sylvia K, Schechter, Clyde, Song, Juhee, Stout, Natasha K, Sun, Liyang P, Trentham-Dietz, Amy   +18 more
core   +1 more source

Lipoplasty-only breast reduction [PDF]

, 2001
L. Earl Gray
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

PersonalizedUS: Interpretable Breast Cancer Risk Assessment with Local Coverage Uncertainty Quantification [PDF]

arXiv
Correctly assessing the malignancy of breast lesions identified during ultrasound examinations is crucial for effective clinical decision-making. However, the current "golden standard" relies on manual BI-RADS scoring by clinicians, often leading to unnecessary biopsies and a significant mental health burden on patients and their families.
arxiv  

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Management of patients with ventriculoperitoneal shunts in breast surgeries

JPRAS Open
Ventriculoperitoneal (VP) shunts often pass through the anterior chest involving the breast parenchyma. Operating on patients with VP shunts necessitates extra caution during breast surgeries.
Osama Darras, Sara Yacoub, Diwakar Phuyal, Steven Bernard, Raffi Gurunian, Sarah N. Bishop   +5 more
doaj  

The role of chorionic gonadotrophin in breast reduction

, 1962
Phillip Lebon
openalex   +1 more source

UK has highest reduction in deaths from lung and breast cancer [PDF]

, 2002
Conor McKenna
openalex   +1 more source