Results 41 to 50 of about 4,282,035 (295)

Application of the Lalonde (Horizontal-Only Scar) Technique Reduction Mammoplasty in Oncoplastic Breast-Conserving Surgery for Asian Patients: A Case Report

Archives of Plastic Surgery
Oncoplastic breast-conserving surgery combines oncological resection with plastic surgery techniques, including reduction mammoplasty, to achieve effective cancer control and superior cosmetic outcomes.
Ryohei Katsuragi, Hisamitsu Zaha, Ayako Koki, Norie Abe   +3 more
doaj   +1 more source

Oncoplastic Breast Reduction: A Systematic Review of Postoperative Complications

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. Breast-conserving therapy with oncoplastic reduction is a useful strategy for partial mastectomy defect reconstruction. The most recently published systematic review of oncoplastic breast reduction outcomes from 2015 showed wound dehiscence ...
Katherine C. Benedict, MD, Madyson I. Brown, BS, Hunter A. Berry, MD, Scott M. Berry, MD, Robert C. O’Brien, PhD, MS, BS, Jared M. Davis, MD, MBA   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Improving the aesthetic outcome of the superomedial pedicle in wise-pattern breast reduction using a suspension "Hammock" flap technique

Egyptian Journal of Plastic and Reconstructive Surgery, 2023
BackgroundSuperomedial pedicle reduction mammoplasty provides satisfactory and symmetrical projection of the lower pole. Its satisfactory outcome cannot be preserved consistently for quite some time.
Ahmad Mohamed, Sherif Abdelmeged, Omar Eldeen Ali   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast [PDF]

, 2008
Introduction To investigate the predictive value of clinical and biological markers for a pathological complete remission after a preoperative dose-dense regimen of doxorubicin and docetaxel, with or without tamoxifen, in primary operable breast cancer ...
Sinn, Hans-Peter, Sibylle Loibl, Jens-Uwe Blohmer, Jörn Hilfrich, Eidtmann, Holger, Jackisch, Christian, Minckwitz, Gunter von, Elisabeth Merkle, Hilfrich, Jörn, Caputo, Angelika, Angelika Caputo, Merkle, Elisabeth, Dan Costa, Serban, Blohmer, Jens-Uwe, Gunter von Minckwitz, Raab, Günter, German Breast Group (GBG), [Study group], Christian Jackisch, Hans-Peter Sinn, Serban D Costa, Holger Eidtmann, Loibl, Sibylle, Manfred Kaufmann, von Minckwitz, Gunter, null null, Günter Raab, Costa, Serban D., Kaufmann, Manfred   +27 more
core   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation

, 2018
Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, lacking effective targeted therapies, and whose underlying mechanisms are still unclear.
Liu, Jingjing, Yang, Qianxi, Zhang, Jin, Hu, Yunhui, Zhao, Hui, Pan, Teng, Liu, Lei, Yagüe, Ernesto   +7 more
core   +1 more source

Risk determination and prevention of breast cancer [PDF]

, 2014
Breast cancer is an increasing public health problem. Substantial advances have been made in the treatment of breast cancer, but the introduction of methods to predict women at elevated risk and prevent the disease has been less successful.
Howell, Anthony; id_orcid, Anderson, Annie, Key, Timothy, Montserat Garcia-Closas, A. Howell (7638146), Saxton, John, M. N. Harvie (7671182), J. M. Saxton (7638221), Annie S Anderson, Saxton, John M, Robert B Clarke, Michelle N Harvie, Evans, Gareth, Key, Timothy J., M. Garcia-Closas (7638116), Garcia-Closas, Montserat, Andy J. Gescher (7671179), Key, TJ, Clarke, Robert; id_orcid, Saxton, JM, D. G. Evans (7608134), Gescher, Andy J, Stephen W Duffy, Key, Timothy J, Clarke, Robert, Harvie, Michelle N., Harvie, Michelle, Anthony Howell, Anderson, Annie S.; id_orcid, Harvie, MN, D Gareth Evans, John M Saxton, Gescher, AJ, Clarke, RB, T. J. Key (7638161), Duffy, Stephen W., Anderson, AS, Anderson, Annie S, R. B. Clarke (7638080), Howell, A, Duffy, SW, Andy J Gescher, Clarke, Robert B., Saxton, John M., Duffy, Stephen W, Evans, Gareth; id_orcid, Duffy, Stephen, S. W. Duffy (7638095), Timothy J Key, Garcia-Closas, M, A. S. Anderson (7638050), Howell, Anthony, Gescher, Andy, Evans, DG, Evans, D. Gareth, Gescher, Andy J.   +55 more
core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source