ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao +12 more
wiley +1 more source
A model for promoting breast self-examination among rural South African women in KwaZulu-Natal. [PDF]
Sarmah N, Sibiya MN, Khoza TE.
europepmc +1 more source
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu +9 more
wiley +1 more source
Knowledge, attitudes, and awareness of breast self-examination among female university students in three Arab countries: a multi-center cross-sectional study. [PDF]
Gamal A +11 more
europepmc +1 more source
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Investigate scale and ways of doing breast self examination (1993)
S faghyeh safaii +3 more
openalex +1 more source
Designing and evaluation of the effect of community-based intervention on breast self-examination among reproductive-aged women in Ethiopia: A Cluster Randomized Controlled Trial. [PDF]
Agide FD +5 more
europepmc +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Breast Self Examination; Significant Tool in Early Detection of Breast Cancer
Saima Khan +3 more
openalex +1 more source
Investigating the effect of mobile learning on breast self-examination in women referring to comprehensive health centers in Mahabad City, Iran. [PDF]
Khoshbakht K, Shakerian S.
europepmc +1 more source

