Results 31 to 40 of about 299,514 (294)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Breast Self-Examination Teaching for Women in Chemical Dependency Programs [PDF]

, 1996
Fifty-two women from 5 chemical dependency programs participated in a 1 hour health education program teaching breast self-examination using breast models.
Lessard Jungwirth, Michelle B.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Persepsi Wanita Berisiko Kanker Payudara Tentang Pemeriksaan Payudara Sendiri di Kota Semarang, Jawa Tengah [PDF]

, 2010
Background: Breast cancer is the main cause of death due to cancer at Semarang City. Breast cancer can be detected through breast self-examination. Perceptions about about benefit as well as perception about constraints of breast self-examination affect ...
Desanti, IM. Sunarsih, Supriyati, Ophi Indria
core  

Does mammographic screening and a negative result affect attitudes towards future breast screening? [PDF]

, 2001
OBJECTIVES:To investigate the impact of an experience of a benign mammographic result on intention to seek medical help immediately in the case of breast abnormalities, and on intentions and thoughts about future participation in screening.
Boer, H., Drossaert, C.H.C., Seydel, E.R.   +2 more
core   +4 more sources

Knowledge of Students Toward Breast Cancer and Breast Self-Examination Practice at High School Nursing in Basra City

Kufa Journal for Nursing Sciences, 2014
Background: Breast cancer is a life threatening disease that can affect women's sense of self-esteem, her sexuality. Globally, breast cancer is the most common cancer among women.
Samira Muhammed Ebrahim
doaj   +1 more source

Knowledge, Attitude and Practice of Breast Cancer Screening in Medical and Non-Medical Females Students of Lahore, Pakistan

Proceedings, 2021
Introduction: Breast cancer is the most common cancer in women all over the world and a leading cause of death in women of Pakistan. Programs promoting awareness about breast cancer, breast self-examination (BSE), clinical breast examination (CBE) and ...
Jawaria Ghazanfar, Ayesha Khalil, Aniqua Tahir, Muhammad Imran Anwar, Hina Mahmood, Ayesha Humayun   +5 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Assessment of the knowledge and attitudes of nursing and midwifery personnel about Breast Self-Examination [PDF]

, 2014
Introduction: Breast cancer is the most common malignancy in women. Monthly breast self-examination is one of the easy and cost-effective methods that does not require specialized personnel and equipment and has been introduced as the best method of ...
Heidari, M., Shahbazi, S.
core