Results 91 to 100 of about 397,872 (340)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

A pixel-based approach to massive lesion detection in X-ray mammography [PDF]

International Congress Series 1281 (2005) 1394, 2005
A system for the automated detection of massive lesions in mammograms is presented. The approach we adopted is a pixel-based and multi-level one. Each pixel in a mammogram is flagged with the appropriate class membership, e.g. massive lesions or normal breast tissue.
arxiv  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

NAT10/ac4C/JunB facilitates TNBC malignant progression and immunosuppression by driving glycolysis addiction

Journal of Experimental & Clinical Cancer Research
Background N4-Acetylcytidine (ac4C), a highly conserved post-transcriptional mechanism, plays a pivotal role in RNA modification and tumor progression. However, the molecular mechanism by which ac4C modification mediates tumor immunosuppression remains ...
Guozheng Li, Xin Ma, Shiyao Sui, Yihai Chen, Hui Li, Lei Liu, Xin Zhang, Lei Zhang, Yi Hao, Zihan Yang, Shuai Yang, Xu He, Qin Wang, Weiyang Tao, Shouping Xu   +14 more
doaj   +1 more source

Independent prognostic impact of preoperative serum carcinoembryonic antigen and cancer antigen 15-3 levels for early breast cancer subtypes

World Journal of Surgical Oncology, 2018
Background Although the prognosis for operable breast cancers is reportedly worse if serum carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels are above normal, the usefulness of this prognosis is limited due to the low sensitivity and
Michiko Imamura, Takashi Morimoto, Takashi Nomura, Shintaro Michishita, Arisa Nishimukai, Tomoko Higuchi, Yukie Fujimoto, Yoshimasa Miyagawa, Ayako Kira, Keiko Murase, Kazuhiro Araki, Yuichi Takatsuka, Koshi Oh, Yoshikazu Masai, Kouhei Akazawa, Yasuo Miyoshi   +15 more
doaj   +1 more source

An inpainting approach to manipulate asymmetry in pre-operative breast images [PDF]

arXiv
One of the most frequent modalities of breast cancer treatment is surgery. Breast surgery can cause visual alterations to the breasts, due to scars and asymmetries. To enable an informed choice of treatment, the patient must be adequately informed of the aesthetic outcomes of each treatment plan.
arxiv  

Significance of liver metastasis in women with disseminated breast cancer undergoing endocrine ablative surgery [PDF]

, 1966
Takuma Nemoto, Thomas L. Dao
openalex   +1 more source

Modern Trends in the Breast Cancer Conserving Surgery and Oncoplastic Breast Surgery

Medical Radiology and radiation safety, 2018
Introduction: The highest priority for modern clinical oncology is functionally-sparing and organ-conserving treatment. In Russia, breast cancer (BC), among all malignant tumors, accounted for 21.1 % of women in 2017. Oncoplastic radical resections (OPS-BCS = oncoplastic surgery – breast conserving surgery) have been widely used.
Zikiryahodjaev A.D., Ermoshchenkova M.V., Kaprin A.D., Chissov V.I., Zapirov G.M.   +4 more
openaire   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

MORF4L2 induces immunosuppressive microenvironment and immunotherapy resistance through GRHL2/MORF4L2/H4K12Ac/CSF1 axis in triple-negative breast cancer

Biomarker Research
Background Although immunotherapy has achieved great progress in advanced triple-negative breast cancer (TNBC), there are still numerous patients who do not benefit from immunotherapy.
Xin-Yi Sui, Shuo-Wen Cao, Xiao-Qing Song, Xi-Yu Liu, Chao Chen, Qingya Yan, Zhi-Qing Wang, Wen-Juan Zhang, Lin-Xiaoxi Ma, Xi Jin, Ding Ma, Yi Xiao, Song-Yang Wu, Ying Xu, Zhi-Ming Shao, Lei Fan   +15 more
doaj   +1 more source