Results 41 to 50 of about 1,314,008 (299)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Stained region lymph node biopsy for axillary restaging after neoadjuvant systemic therapy in node-positive breast cancer: a cohort study

Journal of Cancer Research and Clinical Oncology
Background Accurate assessment of axillary lymph node status after neoadjuvant systemic therapy (NST) is essential for de-escalating surgery in node-positive breast cancer.
Rui Chen, Hailing Zha, Qiannan Zhu, Xinpei Liu, Lifeng Huang, Cuiying Li, Jue Wang, Xiaoming Zha   +7 more
doaj   +1 more source

Clinical application of ultrasound-guided percutaneous microwave ablation for benign breast lesions: a prospective study

BMC Cancer, 2019
Background Background: Benign breast lesions are the most common diseases in adult women, which have been treated with minimally invasive therapies in recent years.
Wei Zhang, Zhan-Qiang Jin, Masoud Baikpour, Jian-Min Li, Hui Zhang, Ting Liang, Xiao-Ming Pan, Wen He   +7 more
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Value of shear wave elastography in evaluating response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis

Journal of International Medical Research
Objective To determine how well shear wave elastography performs as a diagnostic tool for determining the pathological response to neoadjuvant chemotherapy in breast cancer.
Bin Lian, Chuanxin Ye, Fengjie Li, Huotang Qin, Lifang Zhou, Changyuan Wei, Huihui Yang   +6 more
doaj   +1 more source

Reducing Unnecessary Biopsies Using Digital Breast Tomosynthesis and Ultrasound in Dense and Nondense Breasts [PDF]

, 2022
Aim: To compare digital breast tomosynthesis (DBT) and ultrasound in women recalled for assessment after a positive screening mammogram and assess the potential for each of these tools to reduce unnecessary biopsies.
William Rae, Hadadi, Ibrahim, Clarke, J., Ekpo, Ernest, Vincent, Wendy, Wendy Vincent, Rae, W., Ibrahim Hadadi, Jillian Clarke, McEntee, Mark, McEntee, Mark F., Mark McEntee, Clarke, Jillian, Rae, William, Ernest Ekpo, Ekpo, E., Hadadi, I., Vincent, W.   +17 more
core   +1 more source

Autonomous Navigation of Pollen‐Inspired Magnetic Microrobots for Biomedical Applications

Advanced Robotics Research, EarlyView.
A sunflower pollen‐inspired magnetic microrobot enables controlled rolling navigation in vessel‐like environments. Its open geometry reduces hydrodynamic drag, while vision‐based closed‐loop control, shortest‐path planning, and reinforcement learning support target‐reaching and maze navigation with microrobot‐scale accuracy, highlighting a route toward
Ali Anil Demircali, Abdurrahim Yilmaz, Meysam Keshavarz, Jinshi Zhao, Ara Darzi, Eric Yeatman, Burak Temelkuran   +6 more
wiley   +1 more source

Exploring prognostic factors in breast cancer: development and selection of optimal machine learning models

Frontiers in Oncology
ObjectiveTo investigate prognostic factors for breast cancer recurrence and metastasis, and to systematically compare multiple machine learning models to develop an optimal predictive tool.MethodsWe retrospectively analyzed data from 1,056 breast cancer ...
Meiying Shen, Yulei Wang, Zongyuan Wu, Lifei Chen, Shaofeng Wu, Huawen Pan, Bo Xu   +6 more
doaj   +1 more source