Results 91 to 100 of about 193,745 (310)

Whole-body galactose oxidation as a robust functional assay to assess the efficacy of gene-based therapies in a mouse model of Galactosemia

Molecular Therapy: Methods & Clinical Development
Despite the implementation of lifesaving newborn screening programs and a galactose-restricted diet, many patients with classic galactosemia develop long-term debilitating neurological deficits and primary ovarian insufficiency.
Bijina Balakrishnan, Xinhua Yan, Marshall D. McCue, Olivia Bellagamba, Aaron Guo, Felicity Winkler, Jason Thall, Lisa Crawford, Rain Dimen, Sara Chen, Sean McEnaney, Yiman Wu, Mike Zimmer, Joe Sarkis, Paolo G.V. Martini, Patrick F. Finn, Kent Lai   +16 more
doaj   +1 more source

14C triolein breath test: an assessment in the elderly. [PDF]

, 1989
K Mylvaganam, Peter Hudson, Amy H. Herring, C P Williams   +3 more
openalex   +1 more source

Reducing Personalization Time and Energy Cost While Walking Outdoors with a Portable Exosuit

Advanced Robotics Research, EarlyView.
Rapid Real‐World Optimization! An AF‐based human‐in‐the‐loop optimization strategy rapidly personalizes a portable hip extension exosuit for incline walking. Real‐time Bayesian optimization of assistive force significantly reduces metabolic energy—up to 16.2%—while converging in just 3 min 24 s.
Kimoon Nam, Saikat Sahoo, Yoosun Kim, Dongmin Go, Jeongho Choo, Cheonkyu Park, Seungtae Yang, Giuk Lee   +7 more
wiley   +1 more source

GC-MS-based metabolomics of volatile organic compounds in exhaled breath: applications in health and disease. A review

Frontiers in Molecular Biosciences
Exhaled breath analysis, with particular emphasis on volatile organic compounds, represents a growing area of clinical research due to its obvious advantages over other diagnostic tests.
María Bajo-Fernández, Érica A. Souza-Silva, Érica A. Souza-Silva, Coral Barbas, Ma Fernanda Rey-Stolle, Antonia García   +5 more
doaj   +1 more source

Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics

Advanced Robotics Research, EarlyView.
This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang, Zhipeng Jiang, Sun Hwa Kwon, Matthew Ibrahim, Alexander Dang, Lin Dong   +5 more
wiley   +1 more source

Liquid Metal Sensors for Soft Robots

Advanced Robotics Research, EarlyView.
This review thoroughly reviews liquid metal sensors in soft robots. Their unique material properties like high conductivity and good biocompatibility are analyzed. Working principles are classified, and applications in environmental perception, motion detection, and human—robot interaction are introduced.
Qi Zhang, Nan Li, Yujia Song, Chen Hua, Tangzhen Guan, Yibing Ma, Cai Cheng, Jing Liu   +7 more
wiley   +1 more source

Standardizing the ¹³C-Methacetin Breath Test: A Call for Clinical Integration in Liver Function Testing

Livers
Background/Objectives: The 13C-Methacetin Breath Test (MBT) is a non-invasive tool to evaluate hepatic microsomal function via exhaled 13CO2, reflecting cytochrome P450 1A2 (CYP1A2)-mediated metabolism.
Jasmin Weninger, Michael Pohl, Mustafa Özçürümez, Oliver Götze, Ali Canbay   +4 more
doaj   +1 more source

Expanding analytical options in sports drug testing: Mass spectrometric detection of prohibited substances in exhaled breath [PDF]

, 2017
Mario Thevis, Oliver Krug, Hans Geyer, Wilhelm Schänzer   +3 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source