Results 201 to 210 of about 2,717 (260)

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang   +6 more
wiley   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu   +4 more
wiley   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

open access: yesAdvanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora   +11 more
wiley   +1 more source

Christian Bauer-physiologist, mentor, and philosopher. [PDF]

open access: yesPflugers Arch
Kurtz A   +6 more
europepmc   +1 more source

Bending‐Induced Vibrational Landscape Reorganization Governs Energy Dissipation in Perylene Bisimides

open access: yesAngewandte Chemie, EarlyView.
Gradually bent perylene bisimides (PBIs) isolate structural distortion as the sole variable and exhibit negligible intersystem crossing, uncovering rapid vibrational dephasing as the dominant driver of internal conversion through excited‐state vibrational landscape reorganization.
Wei Zhang   +8 more
wiley   +1 more source

Solvent Hydrogen Bonding Determines Adsorption Geometry of Trimesic Acid on Cu

open access: yesAngewandte Chemie, EarlyView.
Water reorients adsorbate molecules. Combined tip‐enhanced Raman spectroscopy, density functional theory and molecular dynamics simulations reveal the adsorption geometry of trimesic acid on Cu. Subtle adsorbate–substrate–solvent energy differences due to hydrogen bonding dictate molecular orientation at solid/liquid and solid/gas interfaces, providing
Anusha Lalitha   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy