Results 241 to 250 of about 18,489 (341)

SDS‐CRISPR for Single‐Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan   +12 more
wiley   +1 more source

The Breathing IQ: an anthropometric index of diaphragmatic breathing efficiency. [PDF]

open access: yesFront Physiol
Vranich B   +11 more
europepmc   +1 more source

Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation

open access: yesAdvanced Science, EarlyView.
Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li   +5 more
wiley   +1 more source

Mechanistic Design of Graphdiyne‐Based Multimodal Sensing Integrating Machine Learning and Photothermal Dynamics for Precision Recognition and On‐Demand Inactivation

open access: yesAdvanced Science, EarlyView.
A triple‐mode theranostic platform enables integrated electrochemical, colorimetric, and photothermal detection of bacterial infection. Glucose oxidation triggers H2O2 generation and TMB oxidation to oxTMB, producing color and thermal signals under 808 nm NIR irradiation.
Jing Xu   +8 more
wiley   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

open access: yesAdvanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border   +3 more
wiley   +1 more source

A Stretchable, Mechanically‐Interlocked Polyrotaxane Hydrogel for Wearable Motion and Electrophysiological Monitoring

open access: yesAdvanced Science, EarlyView.
A mechanically interlocked polyrotaxane hydrogel integrates sliding macrocycles within a covalent network, yielding skin‑like softness, high stretchability, robust adhesion, and stable ionic conductivity. This multifunctional interface enables simultaneous high‑fidelity monitoring of human motion and epidermal electrophysiological signals (ECG/EMG ...
Hao‐Zheng Huang   +9 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

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