Results 161 to 170 of about 160,039 (318)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

MXene/Carboxymethyl Chitosan Moisture Responsive Soft Actuator with Diode‐Like Actuation for Versatile Applications Driven by Human Metabolism

open access: yesAdvanced Science, EarlyView.
A MXene‐based actuator with gradient thickness is fabricated by a novel and simple vacuum‐assisted “tilt‐filtration” approach. The actuator exhibits a “diode‐like” controllable unidirectional deformation behavior under moisture gradient, and its deformation direction is strictly correlated to its thickness gradient direction and moisture source ...
Liangliang Xu   +7 more
wiley   +1 more source

Edible and Recyclable Gelatin‐Based Electronics for High‐Precision Health and Environmental Monitoring

open access: yesAdvanced Science, EarlyView.
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong   +6 more
wiley   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

open access: yesAdvanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan   +12 more
wiley   +1 more source

Effects of Auditory Neuro-feedback Training Using Breathing Exercises on Paramenstrual Symptoms in Young Women

open access: diamond, 2023
Nana MATSUO   +6 more
openalex   +2 more sources

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

open access: yesAdvanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang   +18 more
wiley   +1 more source

Influence of facemask design on operational performance [PDF]

open access: yes
Spirometric measurements of oxygen volume and determination of the amount of argon in exhaled breath are used to analyze facemask design efficiency during treadmill walking tests with subjects carrying plastic hoods filled with argon.
Griffin, O. G., Longson, D. J.
core   +1 more source

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