Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Yoga, Meditation, Breathing Exercises, and Inflammatory Biomarkers with Possible Implications in COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [PDF]
Komal Shah +4 more
openalex +1 more source
A MXene‐based actuator with gradient thickness is fabricated by a novel and simple vacuum‐assisted “tilt‐filtration” approach. The actuator exhibits a “diode‐like” controllable unidirectional deformation behavior under moisture gradient, and its deformation direction is strictly correlated to its thickness gradient direction and moisture source ...
Liangliang Xu +7 more
wiley +1 more source
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong +6 more
wiley +1 more source
The Effectiveness of Manual Therapy in the Cervical Spine and Diaphragm, in Combination with Breathing Re-Education Exercises, on the Range of Motion and Forward Head Posture in Patients with Non-Specific Chronic Neck Pain: A Randomized Controlled Trial [PDF]
Petros I. Tatsios +3 more
openalex +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
Influence of facemask design on operational performance [PDF]
Spirometric measurements of oxygen volume and determination of the amount of argon in exhaled breath are used to analyze facemask design efficiency during treadmill walking tests with subjects carrying plastic hoods filled with argon.
Griffin, O. G., Longson, D. J.
core +1 more source
Effectiveness of Breathing Exercises and Stabilization Techniques on Patients with COVID-19: Quasi-Experimental Study. [PDF]
Jung JH, Lee JW, Ko JY.
europepmc +1 more source

