Results 231 to 240 of about 172,225 (297)

Bile Culture, Antimicrobial Susceptibility, and Hepatobiliary Pathology in Dogs Undergoing Cholecystectomy for Gallbladder Mucocele. [PDF]

Animals (Basel)
Choe JM, Kim H, Hwang J, Kim HY.
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

An integrative, peer-reviewed and open-source cooperative-breeding database (Co-BreeD). [PDF]

J Anim Ecol
Ben Mocha Y, Woith M, Scemama de Gialluly S, Bruscagnin L, Kestel N, Markman S, Drobniak SM, Baglione V, Boersma J, Cousseau L, Covas R, Braga de Miranda GH, Dey CJ, Doutrelant C, Gula R, Heinsohn R, Keynan O, Kingma SA, Leitão AV, Li J, Makuya L, Middleton KM, Pruett-Jones S, Radford AN, Restrepo C, Rubenstein DR, Schradin C, Theuerkauf J, Warrington MH, Williams DA, Woxvold IA, Griesser M.   +31 more
europepmc   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

A legacy of genetic entanglement with wolves shapes modern dogs. [PDF]

Proc Natl Acad Sci U S A
Lin AT, Fairbanks RA, Barba-Montoya J, Liu HL, Kistler L.   +4 more
europepmc   +1 more source

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Genomic insights into the recent evolution and biodiversity of Italian sheep breeds. [PDF]

Mamm Genome
Bionda A, Negro A, Floridia V, Sarti FM, Grande S, Crepaldi P.   +5 more
europepmc   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

A 120-y time series of genomes reveals the consequences of closed breeding in German Shepherd Dogs. [PDF]

Proc Natl Acad Sci U S A
Scarsbrook L, Spatola GJ, Dreger DL, Feuerborn TR, Buckley RM, Carmagnini A, Fabre AC, Harris AC, Hertwig ST, Leeb T, Mousseau TA, Tabbada K, Thalmann O, Larson G, Frantz LAF, Ostrander EA.   +15 more
europepmc   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source