Results 171 to 180 of about 60,672 (258)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang   +14 more
wiley   +1 more source

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

open access: yesAdvanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang   +15 more
wiley   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li   +8 more
wiley   +1 more source

Developing power plant materials using the life cycle lens. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci
Quadling A   +3 more
europepmc   +1 more source

Early Milk Total and Differential Cell Counts as a Diagnostic Tool to Improve Antimicrobial Therapy Protocols. [PDF]

open access: yesAnimals (Basel), 2023
Zecconi A   +6 more
europepmc   +1 more source

A Novel Sparse Cellular Labeling System with Tunable Gradients and Long‐Term Stability

open access: yesAdvanced Science, EarlyView.
The Tri‐M (Multi‐recombinase, Multi‐recognition site, and Multi‐nested) sparse cellular labeling system, built upon competitive recombination, integrates transgenic mice with viral injection to achieve tunable and long‐term stable sparse labeling of specific cell types with region selectivity, from sparse populations to individual cells, facilitating ...
Xiaomei Tang   +17 more
wiley   +1 more source

Potential for Blanket Related Investigations in Riga

open access: yes
Potential for blanket related investigations in ...
Kravalis, Kalvis, Platacis, Ernests
core  

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