Results 231 to 240 of about 138,513 (347)
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Advanced Science, EarlyView.Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
The Cat Is Already Out of the Bag: Humane and Pragmatic Solutions for Cats on Dairy Farms. Reply to Calver et al. It's Premature to Encourage Working Cats for Rodent Control on Australian Dairy Farms. [PDF]
Animals (Basel)Dutton-Regester K +4 more
europepmc +1 more source
Exploitation of a lunar-based nuclear economy: Implications for solar system commerce [PDF]
Hudson, Gary C.
core +1 more source
Advanced Science, EarlyView.CCR2‐Enhanced Macrophage Membrane–Camouflaged Microbubbles for MCP‐1–Mediated Thrombus Targeting and Ultrasound‐Triggered Urokinase Release. ABSTRACT The clinical management of thrombosis, a primary cause of death worldwide, is hampered by the limitations of current thrombolytic agents, including short half‐life and high risk of off‐target bleeding ...
Buying Li +8 more
wiley +1 more source
Direct-fed Microbials (DFM) and Poultry Genomics: A Synergistic Approach to Sustainable Antibiotic Free Farming. [PDF]
Probiotics Antimicrob ProteinsHassan ASI +5 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Inositol pyrophosphates (PP‐InsPs) are central regulators of eukaryotic signaling events. While certain PP‐InsP isomers have been conclusively linked to the regulation of phosphate homeostasis through interaction with SPX domain‐containing proteins in plants, the functions of the recently discovered isomer 4/6‐PP‐InsP5 remain largely unknown ...
Kevin Ritter +10 more
wiley +1 more source
Status of water cooled ceramic breeder blanket development
Status of water cooled ceramic breeder blanket developmentThe development of a Water Cooled Ceramic Breeder (WCCB) Test Blanket Module (TBM) is being performed as one of the most important steps toward fusion DEMO reactor in Japan. As for the ITER-TBM program, the conceptual design of WCCB-TBM system has been approved through design review by the ITER organization, and the activity for preliminary design ...
openaire
Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs
Advanced Science, EarlyView.Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang +13 more
wiley +1 more source