Results 151 to 160 of about 506,342 (292)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Convertible shielding to ceramic breeding blanket

open access: yesConvertible shielding to ceramic breeding blanket
ITERにおける互換性のあるブランケットの候補概念として以下の4つを検討している。(1)増殖材/増倍材分離層状型(2)増殖材/増倍材分離BIT型(3)増殖材/増倍材分離BOT型(4)増殖材/増倍材混合BOT型。これらはすべて増殖材としてセラミクッス及び増倍材としてベリリウムをいずれも小球状ペブルとして使用する。いずれのブランケットもBPPではベリリウムのみ充填して遮蔽性能を確保してEPPに望んで増殖材ペブルを追加充填してトリチウム増殖を行う。ブランケット容器への増殖材の充填方法としては湿式が高充填率及び均一充填率を得るという点で期待できる。一次元核解析の結果ではBOT法が遮蔽及び増殖性能に優れているが最終的にはブランケットの特性との整合及び製作性の点から詳細な検討を行って決定する必要がある。
openaire   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Thermal design of a fusion breeding blanket

open access: yesThermal design of a fusion breeding blanket
国内次期装置の一候補であるスィミングプール型トカマク炉の増殖ブランケットについて熱設計を行なった。ブランケットはチューブインシェルタイプとし、トリチウム増殖領域内Li$_{2}$O温度を400$^{\circ}$C以上、1200$^{\circ}$C以下に保つため、冷却管Li$_{2}$O間にヘリウムガス層を設ける構造とした。又Li$_{2}$O最適ヘリウムギャップおよび最適冷却ピッチを決定した。その結果、ヘリウムギャップは0.75mmとなり、冷却管ピッチは最内列で30mm、最外列で70mmとなった。
openaire   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy