Results 211 to 220 of about 506,342 (292)

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

Staying positive: producing net power. [PDF]

Philos Trans A Math Phys Eng Sci
Acres J, Antoniou I, Christie F, Blackburn D, Blackburn D, Knight S.   +5 more
europepmc   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

A cost-effective proof-of-concept <i>ex vivo</i> perfusion model for myocardial ischemia-reperfusion injury in wistar rats: enhancing accessibility in resource-constrained settings. [PDF]

Front Cardiovasc Med
P S, Satyam SM, Rehman A, Bharati S, Shetty P, El-Tanani M, Ahmed AZ, Kumari R, Albadawi MS, Assaf F, Hashemi SMSM, Khan FA, Doukarli MKA, Robari MMHR, Paryani MJP, Singh VK, S GK.   +16 more
europepmc   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Optimizing wheat development to a range of winter climates. [PDF]

J Exp Bot
Hirsz D, Dixon LE.
europepmc   +1 more source

ITER breeding blanket module design & analysis

ITER breeding blanket module design & analysis
トリチウム増殖材と中性子増倍材をいずれも微小球ペブル状として充填する設計となっているITER増殖ブランケットに対し、とくにペブル充填層の熱・機械特性に着目して汎用熱・構造解析コードABAQUSの特殊計算オプションを使用した熱・機械解析を実施した。また、耐高熱負荷が問題となる第一壁について、Beアーマとステンレス鋼構造材の接合部における熱応力履歴を弾塑性解析により求めると共に、これに基づいて、アーマ/構造材接合部における強度評価方法について検討した。さらに、増殖ブランケット・モジュールの製作に関し、第一壁及び冷却パネル、増殖材充填部等の各構成要素を個々に製作し、それらを組み合わせることを基本として各構成要素の製作方法及び全体組立手順を検討した。
openaire   +1 more source

Biopsychosocial Determinants of Hand Function and Its Trajectories Over Five Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate hand function trajectories over five years in primary hand osteoarthritis (OA). Additionally, determinants of baseline and longitudinal hand function were assessed. Methods A total of 538 patients with both baseline and five‐year study visits were analyzed.
Annemiek V. E. M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Elite donors and stable marker-trait associations for grain iron and zinc biofortification in rice under organic and inorganic production systems. [PDF]

Front Plant Sci
Veeraraj SD, Rajendran K.
europepmc   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source