Results 191 to 200 of about 22,173 (305)

Ocular Symptoms in Pre- and Perimenopausal Woman Infected with <i>Demodex</i> spp. [PDF]

open access: yesPathogens
Kosik-Bogacka D   +7 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Thermal design of a fusion breeding blanket

open access: yesThermal design of a fusion breeding blanket
国内次期装置の一候補であるスィミングプール型トカマク炉の増殖ブランケットについて熱設計を行なった。ブランケットはチューブインシェルタイプとし、トリチウム増殖領域内Li$_{2}$O温度を400$^{\circ}$C以上、1200$^{\circ}$C以下に保つため、冷却管Li$_{2}$O間にヘリウムガス層を設ける構造とした。又Li$_{2}$O最適ヘリウムギャップおよび最適冷却ピッチを決定した。その結果、ヘリウムギャップは0.75mmとなり、冷却管ピッチは最内列で30mm、最外列で70mmとなった。
openaire  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Breeding blanket development; Tritium release from breeder

open access: yesBreeding blanket development; Tritium release from breeder
核融合炉ブランケットを設計するためには、微小球を用いたブランケット構造体の中性子照射に関する工学的データが必要不可欠である。工学的データのうち、トリチウム生成放出特性は、最も重要なデータの1つである。このため、トリチウム増殖材料の候補材であるチタン酸リチウム(Li$_{2}$TiO$_{3}$)微小球からのトリチウム生成放出試験を行い、トリチウム放出特性に対するスイープガス流量,照射温度,スイープガス中の水素添加量,熱中性子束の変化等の効果について調べた。本試験の結果、(1)Li$_{2}$TiO$_{3}$微小球充填体の外壁温度が100$^{\circ}$C以上になった時、トリチウム放出が観測された。また、充填体の外壁温度が300$\sim$400$^{\circ}$Cのとき、トリチウム生成 ...
openaire  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

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