Results 101 to 110 of about 478,542 (302)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Nuclear Materials and EnergyThe control of tritium (3H) in liquid-based tritium breeding blankets (TBBs) is one of the key points to assure their correct performance to prove the 3H sufficiency.
Antonio Hinojo +3 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Tritium technologies for pbli based breeding blankets
, 2013 A lead-lithium based breeding blanket for DEMO and its corresponding Test Blanket Module (TBM) to be tested in ITER is being developed in EU. The same approach is pursued in other countries involved in the development of fusion nuclear technologies.
Ciampichetti, A.
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Habitat selection and breeding ecology of three species of waders in the western isles of Scotland [PDF]
, 1988 The habitat requirements and population dynamics of Redshank, Dunlin and Ringed Plover on internationally important breeding grounds in the Western Isles of Scotland were studied from 1985 to 1987 using individually colour-ringed birds.
Jackson, David B, Jackson, D.B
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2018
, 2018 CGIAR Excellence in Breeding Platform - Plan of Work and Budget for ...
CGIAR Excellence in Breeding Platform
core
Frontiers in Nuclear EngineeringThe competing requirements of fusion breeder blankets and the high dimensionality of their design space necessitate a systematic treatment to map the variations in performance against given objective metrics and to understand the operational envelope. In
Luke Humphrey +4 more
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source