Results 121 to 130 of about 233 (210)
Convertible shielding to ceramic breeding blanket
Convertible shielding to ceramic breeding blanketITERにおける互換性のあるブランケットの候補概念として以下の4つを検討している。(1)増殖材/増倍材分離層状型(2)増殖材/増倍材分離BIT型(3)増殖材/増倍材分離BOT型(4)増殖材/増倍材混合BOT型。これらはすべて増殖材としてセラミクッス及び増倍材としてベリリウムをいずれも小球状ペブルとして使用する。いずれのブランケットもBPPではベリリウムのみ充填して遮蔽性能を確保してEPPに望んで増殖材ペブルを追加充填してトリチウム増殖を行う。ブランケット容器への増殖材の充填方法としては湿式が高充填率及び均一充填率を得るという点で期待できる。一次元核解析の結果ではBOT法が遮蔽及び増殖性能に優れているが最終的にはブランケットの特性との整合及び製作性の点から詳細な検討を行って決定する必要がある。
openaire
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Cylindrical breeding blankets for fusion reactors
Cylindrical breeding blankets for fusion reactorsBlankets with a cylindrical structure have been developed for a water-cooled ceramic breeder concept considering a pipe break inside the blanket container. Most existing studies have examined a box structure for the blanket container. Structural change from a box to a cylinder can decrease in first wall thickness while maintaining the pressure ...
openaire
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
Thermal design of a fusion breeding blanket
Thermal design of a fusion breeding blanket国内次期装置の一候補であるスィミングプール型トカマク炉の増殖ブランケットについて熱設計を行なった。ブランケットはチューブインシェルタイプとし、トリチウム増殖領域内Li$_{2}$O温度を400$^{\circ}$C以上、1200$^{\circ}$C以下に保つため、冷却管Li$_{2}$O間にヘリウムガス層を設ける構造とした。又Li$_{2}$O最適ヘリウムギャップおよび最適冷却ピッチを決定した。その結果、ヘリウムギャップは0.75mmとなり、冷却管ピッチは最内列で30mm、最外列で70mmとなった。
openaire
Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu +11 more
wiley +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source