Results 61 to 70 of about 178,795 (254)
AnimalsNile tilapia (Oreochromis niloticus) aquaculture continues to significantly contribute to the growth of the aquaculture sector in Uganda. However, its production is beset by erratic and unreliable seed supply. Also, most hatcheries practice inbreeding of
Ivan Abaho +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Selection Parameters for Production Traits in a Duroc Population
Scientific Papers Animal Science and Biotechnologies, 2023 The goal of this paper is to estimate the genetic parameters for production traits in a pattern pig line. The estimation of the variance-covariance components is a very important step in animal breeding because these components are necessary for: (1 ...
Razvan Alexandru Popa +7 more
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Julius-Kühn-Archiv, 2016 Ostruthin, a natural bioactive compound mainly occurring in the roots of Peucedanum ostruthium, is the focus of this study. P. ostruthium was collected from twelve locations in the Swiss alpine region and reared in an experimental field, subdivided into ...
McCardell, Jessica Heather +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Scientia Agricola, 2009 Some African species of Brachiaria have been introduced into the Americas and became the most important forage for pastures in the tropics. New cultivars can be obtained either from direct selections from the natural existing variability in the germplasm
Claudicéia Risso-Pascotto +2 more
doaj +1 more source
OVERCOMING JUVENILITY IN AN OLIVE BREEDING PROGRAM
Acta Horticulturae, 2012 Resumen del trabajo presentado en el VI International Symposium on Olive Growing, celebrado en Évora (Portugal) del 09 al 13 de septiembre de 2008.
Moreno Alías, Inmaculada +6 more
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Optimizing the breeding strategy in Vanaraja female parent line chicken by monitoring the genetic variability for the major performance traits [PDF]
Animal BioscienceObjective Vanaraja is a highly successful backyard chicken variety developed by crossing males of Vanaraja male line (PD-1) with females of Vanaraja female line (PD-2). Vanaraja was improved over the generations through selection in parent lines.
Matam Niranjan +5 more
doaj +1 more source