Results 41 to 50 of about 2,300,448 (304)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Breeding success of, & habitat use by, eider ducks [PDF]

open access: yes, 1990
The study covers several facets of the ecology of the Eider ducks of the Northumberland coast between Hadston Carrs and Craster between 9 May and 1 August 1990. Special attention was given to the breeding success of the Coquet island population.
Wilson, Richard J.
core  

Breeding ecology of Nyctanassa violacea, Egretta thula and Egretta caerulea nesting grounds in the Pedreira River, Santa Catarina State

open access: yesBiotemas, 2014
This study aimed to characterize the Pedreira River breeding colony of wading birds and to estimate the breeding success of the species in this area. The study area included the mangrove in the Pedreira River, located next to the port of São Francisco ...
Giulia Caroline Bisinela   +2 more
doaj  

The Importance of Nest Box Placement for Barn Owls (Tyto alba)

open access: yesAnimals, 2022
Nest boxes have been used for years to increase breeding bird numbers for conservation and also in biological pest control projects. Barn owls (Tyto alba) have been used as biological pest control agents for rodents for years, and since nest boxes are ...
Motti Charter, Gabe Rozman
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The Breeding Ecology of Homed Puffins Fratercula comiculata in Alaska. [PDF]

open access: yes, 2001
The Horned Puffin {Fratercula corniculata) is one of three North Pacific puffin species. Horned Puffins almost always nest amongst boulders and in rock crevices.
Harding, Ann Marie Aglionby
core  

Nest Design and Breeding Success: Replicability of Methodologies and Research Findings in Secondary Hole Nesting Passerines

open access: yesBirds
More than 40 hypotheses predict associations between features of nest architecture and at least one measure of reproductive success. However, quantitative studies of reproductive consequences of nest characteristics remain scarce.
Marcel M. Lambrechts, D. Charles Deeming
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Ryegrass breeding - balancing trait priorities [PDF]

open access: yes, 2011
peer-reviewedIn all ryegrass breeding programmes it is necessary to select a range of traits within different cultivar types, varying in ploidy and flowering time.
Stewart, A., Hayes, R.
core   +1 more source

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