Results 131 to 140 of about 24,051,771 (331)
Iris ruthenica Ker-Gawl. (Russian iris) is a perennial, clonal, herbaceous plant that is spread across the degraded mountain grasslands in northern Xinjiang.
Gulinige Tayier +3 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Reproductive biology characteristic of Jatropha curcas (Euphorbiaceae)
Jatropha curcas belongs to family of Euphorbiaceae, and is an important biological tree species for diesel production. The current descriptions of the phenotypic traits for male and female flowers are not comprehensive and there have been no reports ...
Xiu-Rong Wang, Gui-Jie Ding
doaj
Among flowering plants, self‐incompatibility is considered the most efficient system for avoiding self‐fertilization. However, many self‐incompatible plants have also evolved floral mechanisms to reduce sexual conflict.
Sheng Zhang +2 more
doaj +1 more source
Pollinators are needed for the reproduction of Echites umbellatus, and only sphingid moths have mouthparts long enough to reach the nectar at the bottom of the species’ long, twisted floral tube.
Suzanne Koptur +3 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Floral characteristics and butterfly wing pollination of Lycoris aurea
Lycoris aurea is a perennial herbaceous plant with important medicinal and ornamental values in the genus Lycoris Herb, the family Amaryllidaceae. The flower has a spider shape with highly exserted stigmas and anthers, which may represent a unique ...
LIAO Rui, LING Xinyu, WU Yuanhui, ZHU Xingfu*
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source

